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PRDM16 Antibody

PRDM16 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPRDM16
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the PRDM16 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis PRDM16 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9HAZ2
PurityAntigen affinity
Description Functions also as a repressor of TGF-beta signaling, Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism, Isoform 4 may regulate granulocytes differentiation, Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells, Binds DNA and functions as a transcriptional regulator
ImmunogenThis PRDM16 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 771-804 amino acids from the Central region of human PRDM16
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PRDM16 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPRDM16
Short namePRDM16 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePR domain containing 16 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0017053 and transcriptional repressor complex and cellular component this GO :0022008 and neurogenesis and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030853 and negative regulation of granulocyte differentiation and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0043457 and regulation of cellular respiration and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043586 and tongue development and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0050872 and white fat cell differentiation and biological process this GO :0050873 and brown fat cell differentiation and biological process this GO :0060021 and palate development and biological process, PRDM16 and IDBG-634734 and ENSBTAG00000018965 and 100137803, PRDM16 and IDBG-86547 and ENSG00000142611 and 63976, Prdm16 and IDBG-207046 and ENSMUSG00000039410 and 70673, metal ion binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003676: nucleic acid binding, this GO :0003676: nucleic acid binding and also this GO :0003677: DNA binding and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0046332: SMAD binding and also this GO :0046872: metal ion binding, this GO :0003677: DNA binding, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0043565: sequence-specific DNA binding, this GO :0046332: SMAD binding, this GO :0046872: metal ion binding, PR domain containing 16
Identity 14000
Gene PRDM16
Long gene name PR/SET domain 16
Synonyms gene name PR domain containing 16 PR domain 16
Synonyms MEL1 PFM13 KIAA1675 MGC166915 KMT8F
Synonyms name MDS1/EVI1-like PR-domain zinc finger protein 16 transcription factor MEL1
Locus 1p36, 32
Discovery year 2000-11-28
GenBank acession AF294278
Entrez gene record 63976
Pubmed identfication 11050005 27151440
RefSeq identity NM_022114
Classification Lysine methyltransferases Zinc fingers C2H2-type PR/SET domain family
Havana BLAST/BLAT OTTHUMG00000000581

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