Name : PRMT5 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN7585418070
| Long name | FITC Conjugated, PRMT5 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PRMT5 |
| Specificity | This is a highly specific antibody against PRMT5 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PRMT5 |
| Gene ID number | 10419 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | May be part of a pathway that is connected to a chloride current, May play a role in cytokine-activated transduction pathways, May regulate the SUPT5H transcriptional elongation properties, Methylates RPS10, Methylates SUPT5H, Methylates histone H2A and H4 'Arg-3' during germ cell development, Methylates histone H3 'Arg-8', Methylates the Piwi proteins (PIWIL1, Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro, Negatively regulates cyclin E1 promoter activity and cellular proliferation, PIWIL2 and PIWIL4), Plays a role in the assembly of snRNP core particles, Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage, possibly through cytoskeletal rearrangement, such methylation being required for the assembly and biogenesis of snRNP core particles, which may repress transcription, with a preference for the formation of MMA, Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | SKB1Hs |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PRMT5 Conjugated |
| Short name | FITC Conjugated, PRMT5 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, PRMT5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10894 |
| Gene | PRMT5 |
| Long gene name | protein arginine methyltransferase 5 |
| Synonyms gene | HRMT1L5 SKB1 |
| Synonyms gene name | pombe) , pombe) homolog SKB1 homolog (S, skb1 (S |
| Locus | 14q11, 2 |
| Discovery year | 1999-06-18 |
| GenBank acession | AF015913 |
| Entrez gene record | 10419 |
| Pubmed identfication | 9843966 |
| Classification | Protein arginine methyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000028709 |