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PSCDBP/CYTIP Antibody, FITC Conjugated

PSCDBP/CYTIP Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PSCDBP/CYTIP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPSCDBP/CYTIP
SpecificityThis is a highly specific antibody against PSCDBP/CYTIP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PSCDBP/CYTIP
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Additionally, After membrane translocation, CYTIP associates with SNX27 (sorting nexin 27) and helps to coordinate trafficking and signaling complexes, CYTIP can be re-located to the cytoplasm via exposure to a phorbol ester, CYTIP can be recruited from the cytoplasm to the membrane by leukocyte integrins which interact with CYTIP through its PDZ domain, CYTIP is able to sequester it to the cytoplasm, CYTIP regulates the activity of cytohesin-1 (an integrin-activating protein involved in cell adhesion) by mediating its recruitment to the leukocyte membrane, Expressed primarily in hematopoetic cells, Through its ability to bind cytohesin-1, Up-regulation of CYTIP is observed in maturing dendritic cells, suggesting a possible role in developmentally-controlled cell adhesion, thereby preventing cytohesin-1 translocation to lymphocytes and interrupting the flow of information in the cell adhesion pathway, CYTIP is a cytoplasmic protein that is involved in lymphocytic cell adhesion
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms B3-1 HE CYBR CASP CYTHIP
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPSCDBP/CYTIP Conjugated
Short name FITC Conjugated, PSCDBP/CYTIP Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PSCDBP/cytohesin 1 interacting protein (Antibody to)
Alternative techniqueantibodies
Alternative to gene target B3-1 and CASP and CYBR and CYTHIP and HE and PSCDBP, CYTIP and IDBG-641611 and ENSBTAG00000008329 and 540450, CYTIP and IDBG-72874 and ENSG00000115165 and 9595, Cytip and IDBG-171958 and ENSMUSG00000026832 and 227929, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005769 and early endosome and cellular component this GO :0005938 and cell cortex and cellular component this GO :0030155 and regulation of cell adhesion and biological process this GO :0045087 and innate immune response and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, cytohesin 1 interacting protein
Identity 9506
Gene CYTIP
Long gene name cytohesin 1 interacting protein
Synonyms gene PSCDBP
Synonyms gene name Sec7 and coiled-coil domains, binding protein , pleckstrin homology
Synonyms name cytohesin binding protein HE cytohesin binder and regulator
Locus 2q24, 1
Discovery year 1999-07-19
GenBank acession L06633
Entrez gene record 9595
Pubmed identfication 18926288 10343115 11867758 20530790 21562043
RefSeq identity NM_004288
Classification PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000154551

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