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PTF1A Antibody

PTF1A Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePTF1A Primary Polyclonal Antibody
Also known asPTF1A PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPTF1A
SpecificityThis is a highly specific antibody against PTF1A
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PTF1A
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Localizing to the nucleus, Loss of functional PTF1 can cause pancreatic progenitors to take on the normal fates of duodenal epithelia, Mutations in the gene encoding PTF1 lead to diabetes mellitus and cerebellar hypoplasia/agenesis, PTF1 contains one basic helix-loop-helix (bHLH) domain and is believed to play an important role in mammalian pancreatic development, PTF1 interacts with RBP-Jâ, a key regulator of pancreatic islet development and insulin gene transcription in beta-cells, and, functioning as a transcription factor that regulates the specification of all three pancreatic cell types, suggesting that PTF1 also plays and important role in cerebellar neurogenesis, they cooperate in regulating the expression of PDX-1 (pancreas/duodenum homeobox protein 1), together, &hellip, ¹, PTF1 is a pancreas-specific protein that functions as a component of the trimeric pancreas transcription factor 1 (PTF1) complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Class A basic helix-loop-helix protein 29, Class II bHLH protein PTF1A, Exocrine pancreas specic transcription factor p48, PTF 1A, PTF1 p48, PTF1-p48, PTF1A_HUMAN, PTF1P48, Pancreas specic transcription factor 1a, Pancreas transcription factor 1 subunit alpha, Pancreas-specic transcription factor 1a, Ptf1a, bHLH transcription factor p48, bHLHa29, p48 DNA binding subunit of transcription factor PTF1, p48 DNA-binding subunit of transcription factor PTF1, PTF1-p48
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPTF1A
Short namePTF1A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePTF1A (Antibody to)
Alternative techniqueantibodies
Identity 23734
Gene PTF1A
Long gene name 1a , pancreas specific transcription factor
Synonyms PTF1-p48 bHLHa29
Locus 10p12, 2
Discovery year 2003-12-04
GenBank acession BK000272
Entrez gene record 256297
Pubmed identfication 8703005
RefSeq identity NM_178161
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000017815

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