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PTP1B Antibody, FITC Conjugated

PTP1B Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, PTP1B Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPTP1B
SpecificityThis is a highly specific antibody against PTP1B
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range13-65/435
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human PTP-1B
Gene ID number5770
Swiss ProtP18031
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET, May play an important role in CKII- and p60c-src-induced signal transduction cascades, May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion, Mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK, Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPTP1B Conjugated
Short name FITC Conjugated, PTP1B Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PTP1B (Antibody to)
Alternative techniqueantibodies
Identity 9642
Gene PTPN1
Long gene name non-receptor type 1 , protein tyrosine phosphatase
Synonyms gene PTP1B
Locus 20q13, 13
Discovery year 1991-09-13
Entrez gene record 5770
Pubmed identfication 2164224
Classification Protein tyrosine phosphatases, non-receptor type
Havana BLAST/BLAT OTTHUMG00000032729

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