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PTPN2 Antibody

PTPN2 Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPTPN2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the PTPN2 antibody should be determined by the researcher
Intented useThis PTPN2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P17706
PurityAntigen affinity
Description Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, Members of the PTP family share a highly conserved catalytic motif, Multiple alternatively spliced transcript variants encoding different isoforms have been found, PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family, Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, and oncogenic transformation, differentiation, have been reported, mitotic cycle, respectively, which is essential for the catalytic activity, which suggested the roles in growth factor mediated cell signaling, TCPTP is also called as PTPN2
ImmunogenAmino acids 1-330 of human PTPN2 were used as the immunogen for the PTPN2 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PTPN2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
LocalizationNuclear
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPTPN2
Short namePTPN2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePTPN2 (Antibody to)
Alternative techniqueantibodies
Identity 9650
Gene PTPN2
Long gene name non-receptor type 2 , protein tyrosine phosphatase
Synonyms gene PTPT
Synonyms TCELLPTP TC-PTP TCPTP
Locus 18p11, 21
Discovery year 1991-09-13
GenBank acession M25393
Entrez gene record 5771
Pubmed identfication 2164224
RefSeq identity NM_002828 NM_080422 NM_080423
Classification Protein tyrosine phosphatases, non-receptor type
Havana BLAST/BLAT OTTHUMG00000131702

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