| Alternative name1 | Anti-PTPRC Polyclonal Antibody |
| Alternative name2 | PTPRC PAb |
| Alternative name3 | PTPRC Polyclonal Antibody |
| Alternative name4 | PTPRC |
| Alternative name5 | CD45, CD45R, GP180, LCA, LY5, T200, B220 |
| Other names | C, CD45 antigen, CD_antigen: CD45, L-CA, Leukocyte common antigen, Receptor-type tyrosine-protein phosphatase C, T200, T200 glycoprotein, T200 leukocyte common antigen, c polypeptide, protein tyrosine phosphatase, protein tyrosine phosphatase, receptor type, receptor type, receptor-type tyrosine-protein phosphatase C, Receptor-type tyrosine-protein phosphatase C |
| Gene name | PTPRC |
| Gene name synonims | N/A |
| Other gene names | B220, CD45, CD45, CD45R, GP180, L-CA, L-CA, LCA, LY5, PTPRC, T200, PTPRC |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | N/A |
| Purification method | Affinity Purification |
| Form/Appearance | N/A |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | 50% glycerol, Buffer: PBS with 0, Cycles of freeze/thaw should be avoided in order to retain the full activity, for long term storage, keep at -80 degrees Celsius, pH7, 02% sodium azide, 3, For short term storage keep at -20 degrees Celsius |
| Tested for: | Immunohistochemistry (IHC), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PTPRC |
| Short name | PTPRC Polyclonal Antibody |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Alternative name | C polyclonal (Antibody to), receptor classification, protein tyrosine phosphatase |
| Alternative technique | polyclonals |
| Alternative to gene target | B220 and CD45 and CD45R and GP180 and L-CA and LCA and LY5 and T200, C, Cell surfaces, PTPRC and IDBG-105609 and ENSG00000081237 and 5788, PTPRC and IDBG-638670 and ENSBTAG00000023144 and 407152, Ptprc and IDBG-195821 and ENSMUSG00000026395 and 19264, heparan sulfate proteoglycan binding, receptor type, this GO :0000187 and activation of MAPK activity and biological process this GO :0001915 and negative regulation of T cell mediated cytotoxicity and biological process this GO :0001916 and positive regulation of T cell mediated cytotoxicity and biological process this GO :0001960 and negative regulation of cytokine-mediated signaling pathway and biological process this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0002378 and immunoglobulin biosynthetic process and biological process this GO :0002711 and positive regulation of T cell mediated immunity and biological process this GO :0002923 and regulation of humoral immune response mediated by circulating immunoglobulin and biological process this GO :0002925 and positive regulation of humoral immune response mediated by circulating immunoglobulin and biological process this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005001 and transmembrane receptor protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006470 and protein dephosphorylation and biological process this GO :0006933 and negative regulation of cell adhesion involved in substrate-bound cell migration and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007411 and axon guidance and biological process this GO :0008201 and heparin binding and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010332 and response to gamma radiation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031953 and negative regulation of protein autophosphorylation and biological process this GO :0034113 and heterotypic cell-cell adhesion and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042100 and B cell proliferation and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0043395 and heparan sulfate proteoglycan binding and molecular function this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0044770 and cell cycle phase transition and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045577 and regulation of B cell differentiation and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0045588 and positive regulation of gamma-delta T cell differentiation and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0048539 and bone marrow development and biological process this GO :0048864 and stem cell development and biological process this GO :0050732 and negative regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0050855 and regulation of B cell receptor signaling pathway and biological process this GO :0050857 and positive regulation of antigen receptor-mediated signaling pathway and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051607 and defense response to virus and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071944 and cell periphery and cellular component this GO :2000473 and positive regulation of hematopoietic stem cell migration and biological process this GO :2000648 and positive regulation of stem cell proliferation and biological process this GO :2001236 and regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0004725: protein tyrosine phosphatase activity, this GO :0004725: protein tyrosine phosphatase activity and also this GO :0005001: transmembrane receptor protein tyrosine phosphatase activity and also this GO :0005515: protein binding and also this GO :0008201: heparin binding and also this GO :0016791: phosphatase activity and also this GO :0019901: protein kinase binding and also this GO :0043395: heparan sulfate proteoglycan binding, this GO :0005001: transmembrane receptor protein tyrosine phosphatase activity, this GO :0005515: protein binding, this GO :0008201: heparin binding, this GO :0016791: phosphatase activity, this GO :0019901: protein kinase binding, this GO :0043395: heparan sulfate proteoglycan binding, protein tyrosine phosphatase |
| Identity | 9666 |
| Gene | PTPRC |
| Long gene name | protein tyrosine phosphatase, receptor type C |
| Synonyms gene | CD45 |
| Synonyms | LCA T200 GP180 |
| Locus | 1q31, 1 , 3-q32 |
| Discovery year | 1986-01-01 |
| GenBank acession | Y00062 |
| Entrez gene record | 5788 |
| Pubmed identfication | 2169617 |
| RefSeq identity | NM_002838 |
| Classification | Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT | OTTHUMG00000035702 |
| Locus Specific Databases | PTPRCbase: Mutation registry for CD45 deficiency LRG_95 |
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