Name : Raptor (Ser792) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN3327980230
| Long name | Raptor (Ser792) Primary Polyclonal Antibody |
| Also known as | Raptor (Ser792) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Raptor Ser792 |
| Specificity | This is a highly specific antibody against Raptor Ser792 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser792 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from mouse Raptor around the phosphorylation site of Ser792 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro, RNAi of C, Rapamycin or amino acid withdrawal increases, Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha, The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, Thus, and it strongly enhances the mTOR kinase activity toward p70alpha, elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1), raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose, whereas insulin strongly inhibits, mTOR controls cell growth |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | KIAA1303, P150 target of rapamycin TOR-scaffold protein, RPTOR_HUMAN, Raptor phospho Ser792, Regulatory Associated Protein of mTOR, Regulatory-associated protein of mTOR, p-Raptor Ser792, p150 target of rapamycin TOR scaffold protein containing WD repeats, p150 target of rapamycin TOR-scaffold protein, ARaptor phospho S792 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Raptor (Ser792) |
| Short name | Raptor (Ser792) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Raptor (Ser792) (Antibody to) |
| Alternative technique | antibodies |