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RAT ANTI MOUSE TREM-1 Antibody

RAT ANTI MOUSE TREM-1 Antibody size: 100ug 343

Supplier MBS MONO
Price 343
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asTREM-1
Other names N/A, Triggering receptor expressed on myeloid cells 1, triggering receptor expressed in monocytes 1, triggering receptor expressed on myeloid cells 1, triggering receptor expressed on myeloid cells 1, triggering receptor expressed on myeloid cells 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameTREM-1
Gene name synonimsN/A
Other gene names N/A, TREM-1, Trem1, Trem1
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
Clone2A12, 3A12, L5-B8
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity , It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, Microbial infection also induces the release of soluble form of TREM-1 from monocytes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, TREM-1 is involved in the microbial inflammatory response, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_TREM-1 mediates the septic shock pathway, a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response, which is reported to act as an inhibitor of TREM-1, TREM-1 This item recognises mouse triggering receptor expressed on myeloid cells 1 (TREM-1)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistology - Frozen (IHC), Western Blot (WB)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetTREM-1
Short nameRAT ANTI MOUSE TREM-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAT antibody to MOUSE TREM-1 (Antibody to)
Alternative techniqueantibodies
Identity 17760
Gene TREM1
Long gene name triggering receptor expressed on myeloid cells 1
Synonyms TREM-1 CD354
Locus 6p21, 1
Discovery year 2002-08-09
GenBank acession AF196329
Entrez gene record 54210
Pubmed identfication 11922939 10799849
RefSeq identity NM_018643
Classification CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000014674

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