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RAT ANTI MOUSE TREM-2 Antibody

RAT ANTI MOUSE TREM-2 Antibody size: 100ug 277

Supplier MBS MONO
Price 277
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asTREM-2
Other names Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2, triggering receptor expressed on monocytes 2, triggering receptor expressed on myeloid cells 2, triggering receptor expressed on myeloid cells 2, triggering receptor expressed on myeloid cells 2a, triggering receptor expressed on myeloid cells 2b, triggering receptor expressed on myeloid cells 2c, triggering receptor expressed on myeloid cells 2 isoform 2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameTREM-2
Gene name synonimsN/A
Other gene names TREM-2, TREM-2, Trem2, Trem2a, Trem2a, Trem2b, Trem2b, Trem2c, Trem2c, Trem2
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone18, 78
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity Clone 78, It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Stimulation of TREM-2 with clone 78, TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells, TREM-2 may also have a functional role in osteoclast formation, This particular antibody might cross react with speacies outside of the listed ones, an activating receptor of the Ig superfamily, 18 enhances multinucleated osteoclast formation in vitro, 18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts, TREM-2 This item recognises Triggering receptor expressed on myeloid cells 2 (TREM-2)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetTREM-2
Short nameRAT ANTI MOUSE TREM-2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAT antibody to MOUSE TREM-2 (Antibody to)
Alternative techniqueantibodies
Identity 17761
Gene TREM2
Long gene name triggering receptor expressed on myeloid cells 2
Synonyms gene name triggering receptor expressed on myeloid cells 2a
Synonyms TREM-2 Trem2a Trem2b Trem2c
Locus 6p21, 1
Discovery year 2002-08-09
GenBank acession AF213457
Entrez gene record 54209
Pubmed identfication 10799849 12080485
RefSeq identity NM_018965
Classification V-set domain containing
Havana BLAST/BLAT OTTHUMG00000014671
Locus Specific Databases LRG_631

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