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Recombinant Mouse Activin Receptor IB, Activin RIB, ALK-4, ACVR1B (C-Fc)

Recombinant Mouse Activin Receptor IB, Activin RIB, ALK-4, ACVR1B (C-Fc) size: 1 mg 1877

Supplier NOVO
Price 1877
Size 1 mg
Reacts withMouse
Source proteins, Recombinants or rec
DescriptionRecombinant Mouse Activin Receptor IB is produced by our Mammalian expression system and the target gene encoding Leu32-Glu126 is expressed with a Fc tag at the C-terminus
Molecular Weight37, 7 kD
UniProt numberQ61271
State of the productFreeze-dried
Shipping conditionsAmbient temperature
Formulation2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0, pH7
Storage recommendations -20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at <
Reconstitution Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml
Purity and determined by Polyacrylamide gel electrophoresis, Greater than 95%
Sequence of the amino acidLLCACTSCLQTNYTCETDGACMVSIFNLDGVEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYIDFCNKIDLRVPSGHLKEPAHPSMWGPVEVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
Levels of endotoxin11 IEU/ug, LAL test shows less than than 0
Test A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or 
Latin nameMus musculus
Grouprecombinants
Gene target ACVR1B (C-Fc), ALK-4, Activin RIB, Activin Receptor IB
Short name ACVR1B (C-Fc), ALK-4, Activin RIB, Recombinant Mouse Activin Receptor IB
Technique E, coli recombinant proteins are , mouses, novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli
Species Mouses, Mouse
Alternative name Activin RIB, activin A receptor, anaplastic lymphoma receptor tyrosine kinase-4, classification IB (C-fragment c), recombinant Mouse Activin Receptor IB
Alternative techniquerec
Alternative to gene target ACTRIB and ACVRLK4 and ALK4 and SKR2, ACVR1B and IDBG-33695 and ENSG00000135503 and 91, ACVR1B and IDBG-632110 and ENSBTAG00000013555 and 539315, ALK and IDBG-42084 and ENSG00000171094 and 238, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642, Acvr1b and IDBG-185560 and ENSMUSG00000000532 and 11479, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, CD246 and NBLST3, Cell surfaces, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007178 and transmembrane receptor protein serine/threonine kinase signaling pathway and biological process this GO :0007417 and central nervous system development and biological process this GO :0009966 and regulation of signal transduction and biological process this GO :0009986 and cell surface and cellular component this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0016020 and membrane and cellular component this GO :0016361 and activin receptor activity, Plasma membranes, activin receptor activity, anaplastic lymphoma receptor tyrosine kinase, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001942 and hair follicle development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006355 and regulation of transcription, this GO :0000187 and activation of MAPK activity and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004704 and NF-kappaB-inducing kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004675: transmembrane receptor protein serine/threonine kinase activity and also this GO :0004702: receptor signaling protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005024: transforming growth factor beta-activated receptor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016361: activin receptor activity, this GO :0004672: protein kinase activity and also this GO :0004704: NF-kappaB-inducing kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004675: transmembrane receptor protein serine/threonine kinase activity, this GO :0004702: receptor signaling protein serine/threonine kinase activity, this GO :0004704: NF-kappaB-inducing kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0005024: transforming growth factor beta-activated receptor activity, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0005524: ATP binding, this GO :0016361: activin receptor activity, this GO :0016772: transferase activity, this GO :0016772: transferase activity, this GO :0017002: activin-activated receptor activity, this GO :0019838: growth factor binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0034711: inhibin binding, this GO :0046332: SMAD binding, this GO :0046872: metal ion binding, this GO :0048185: activin binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017002: activin-activated receptor activity and also this GO :0019838: growth factor binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0034711: inhibin binding and also this GO :0046332: SMAD binding and also this GO :0046872: metal ion binding and also this GO :0048185: activin binding, transferring phosphorus-containing groups and molecular function this GO :0017002 and activin-activated receptor activity and molecular function this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032924 and activin receptor signaling pathway and biological process this GO :0032927 and positive regulation of activin receptor signaling pathway and biological process this GO :0034711 and inhibin binding and molecular function this GO :0038092 and nodal signaling pathway and biological process this GO :0045648 and positive regulation of erythrocyte differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046545 and development of primary female sexual characteristics and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048185 and activin binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :1901165 and positive regulation of trophoblast cell migration and biological process, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0038061 and NIK/NF-kappaB signaling and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0046777 and protein autophosphorylation and biological process this GO :0048666 and neuron development and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, type I, type I and also this GO :0016772: transferase activity, type I and molecular function this GO :0016772 and transferase activity, type IB, activin A receptor
Identity 172
Gene ACVR1B
Long gene name activin A receptor type 1B
Synonyms gene ACVRLK4
Synonyms gene name activin A receptor, type IB
Synonyms ALK4 SKR2 ActRIB
Locus 12q13, 13
Discovery year 1994-12-12
Entrez gene record 91
Pubmed identfication 8397373
RefSeq identity NM_020328
Classification Type 1 receptor serine/threonine kinases
Havana BLAST/BLAT OTTHUMG00000167920

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