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Recombinant Mouse ICOS Ligand, B7-H2, CD275 (C-6His)

Recombinant Mouse ICOS Ligand, B7-H2, CD275 (C-6His) size: 1 mg 2283

Supplier NOVO
Price 2283
Size 1 mg
Reacts withMouse
Source proteins, Recombinants or rec
Description Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling
Molecular Weight1 kD, 27
UniProt numberQ9JHJ8
State of the productFreeze-dried
Shipping conditionsAmbient temperature
Formulation pH7, 2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0
Storage recommendations -20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at <
Reconstitution Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml
Purity and determined by Polyacrylamide gel electrophoresis, Greater than 95%
Sequence of the amino acidETEVGAMVGSNVVLSCIDPHRRHFNLSGLYVYWQIENPEVSVTYYLPYKSPGINVDSSYKNRGHLSLDSMKQGNFSLYLKNVTPQDTQEFTCRVFMNTATELVKILEEVVRLRVAANFSTPVISTSDSSNPGQERTYTCMSKNGYPEPNLYWINTTDNSLIDTALQNNTVYLNKLGLYDVISTLRLPWTSRGDVLCCVENVALHQNITSISQAESFTGNNTKNPQETHNNELKHHHHHH
Levels of endotoxin11 IEU/ug, LAL test shows less than than 0
Test A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or 
Latin nameMus musculus
Grouprecombinants
Gene target B7-H2, CD275 (C-6His), ICOS Ligand
Short name B7-H2, CD275 (C-6His), Recombinant Mouse ICOS Ligand
Technique E, coli recombinant proteins are , mouses, novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli
Species Mouses, Mouse
Alternative name B7-H2, CD275 (C-6His), recombinant Mouse inducible T-cell co-stimulator Ligand
Alternative techniquerec
Alternative to gene target Extracellular, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026, ICOS and IDBG-79246 and ENSG00000163600 and 29851, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, protein binding, this GO :0002517 and T cell tolerance induction and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031295 and T cell costimulation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, inducible T-cell co-stimulator
Identity 17087
Gene ICOSLG
Long gene name inducible T-cell costimulator ligand
Synonyms gene ICOSL
Synonyms KIAA0653 GL50 B7-H2 B7RP-1 B7H2 B7RP1 ICOS-L CD275
Synonyms name B7-related protein 1 B7 homologue 2 B7 homolog 2
Locus 21q22, 3
Discovery year 2003-12-12
GenBank acession AB014553
Entrez gene record 23308
Pubmed identfication 9734811 11007762
RefSeq identity NM_015259
Classification Endogenous ligands C2-set domain containing CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000086920

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