| Reacts with | Mouse |
| Source | proteins, Recombinants or rec |
| Description | Recombinant Mouse Tyrosine Protein Kinase Receptor TYRO3 is produced by our Mammalian expression system and the target gene encoding Ala31-Ser418 is expressed with a Fc tag at the C-terminus |
| Molecular Weight | 68, 9 kD |
| UniProt number | P55144 |
| State of the product | Freeze-dried |
| Shipping conditions | Ambient temperature |
| Formulation | pH 7, 2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0 |
| Storage recommendations | -20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution | Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity | and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid | AGLKLMGAPVKMTVSQGQPVKLNCSVEGMEDPDIHWMKDGTVVQNASQVSISISEHSWIGLLSLKSVERSDAGLYWCQVKDGEETKISQSVWLTVEGVPFFTVEPKDLAVPPNAPFQLSCEAVGPPEPVTIYWWRGLTKVGGPAPSPSVLNVTGVTQRTEFSCEARNIKGLATSRPAIVRLQAPPAAPFNTTVTTISSYNASVAWVPGADGLALLHSCTVQVAHAPGEWEALAVVVPVPPFTCLLRNLAPATNYSLRVRCANALGPSPYGDWVPFQTKGLAPARAPQNFHAIRTDSGLILEWEEVIPEDPGEGPLGPYKLSWVQENGTQDELMVEGTRANLTDWDPQKDLILRVCASNAIGDGPWSQPLVVSSHDHAGRQGPPHSRTSVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Levels of endotoxin | 11 IEU/ug, LAL test shows less than than 0 |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Group | recombinants |
| Gene target | DTK (C-Fc), Tyrosine-Protein Kinase Receptor TYRO3 |
| Short name | DTK (C-Fc), Recombinant Mouse Tyrosine-Protein Kinase Receptor TYRO3 |
| Technique | E, coli recombinant proteins are , mouses, novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species | Mouses, Mouse |
| Alternative name | DTK (C-fragment c), recombinant Mouse Tyrosine-Protein phosphorylation catalyst Receptor TYRO3 protein tyrosine kinase |
| Alternative technique | rec |
| Alternative to gene target | BYK and Dtk and RSE and Sky and Tif, TYRO3 and IDBG-646302 and ENSBTAG00000001694 and 788224, TYRO3 and IDBG-7206 and ENSG00000092445 and 7301, Tyro3 and IDBG-199993 and ENSMUSG00000027298 and 22174, nuclei, this GO :0001779 and natural killer cell differentiation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007283 and spermatogenesis and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0004716: receptor signaling protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0004716: receptor signaling protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0043548: phosphatidylinositol 3-kinase binding, this GO :0046982: protein heterodimerization activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0043548: phosphatidylinositol 3-kinase binding and also this GO :0046982: protein heterodimerization activity, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0021885 and forebrain cell migration and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030168 and platelet activation and biological process this GO :0032940 and secretion by cell and biological process this GO :0034122 and negative regulation of toll-like receptor signaling pathway and biological process this GO :0034446 and substrate adhesion-dependent cell spreading and biological process this GO :0042698 and ovulation cycle and biological process this GO :0043277 and apoptotic cell clearance and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0051250 and negative regulation of lymphocyte activation and biological process this GO :0060068 and vagina development and biological process this GO :0070050 and neuron cellular homeostasis and biological process this GO :0070527 and platelet aggregation and biological process, TYRO3 protein tyrosine kinase |
| Identity | 12446 |
| Gene | TYRO3 |
| Long gene name | TYRO3 protein tyrosine kinase |
| Synonyms gene | RSE |
| Synonyms | Dtk Brt Tif Sky Etk-2 Rek |
| Locus | 15q15, 1 |
| Discovery year | 1992-10-02 |
| GenBank acession | D50479 |
| Entrez gene record | 7301 |
| Pubmed identfication | 7851890 |
| Classification | Fibronectin type III domain containing I-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000130341 |
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