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RGMA Antibody

RGMA Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRGMA Primary Polyclonal Antibody
Also known asRGMA PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRGMA
SpecificityThis is a highly specific antibody against RGMA
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range340-390/450
Subcellular locationCell membrane
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule A
Gene ID number56963
Swiss ProtQ96B86
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, Furthermore, It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway, Regulates cephalic neural tube closure, SMAD5, and SMAD8, and the formation of mature synapses, inhibits neurite outgrowth and cortical neuron branching, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition, Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names RGM domain family member A, RGMA, Repulsive guidance molecule A, RGM
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRGMA
Short nameRGMA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRGMA (Antibody to)
Alternative techniqueantibodies
Identity 30308
Gene RGMA
Long gene name repulsive guidance molecule family member a
Synonyms gene name RGM domain family, member A
Synonyms RGM RGMa
Locus 15q26, 1
Discovery year 2004-02-04
GenBank acession AL390083
Entrez gene record 56963
Pubmed identfication 15975920
RefSeq identity NM_020211
Havana BLAST/BLAT OTTHUMG00000171781

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