| Long name | RIN1 Primary Polyclonal Antibody |
| Also known as | RIN1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | RIN1 |
| Specificity | This is a highly specific antibody against RIN1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RIN1 |
| Gene ID number | 9610 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling, It may function as a guanine nucleotide exchange factor in activation of Rab5a, It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, Rin1 also competes with RAF1 for binding of the activated form of Ras, and has been implicated as a tumor supressor gene in breast cancer, RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | RIN 1, RIN1_HUMAN, Ras inhibitor JC99, Ras interaction/interference protein 1, ras inhibitor, ras inhibitor 1, ras inhibitor RIN1, Ras and Rab interactor 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RIN1 |
| Short name | RIN1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Ras and Rab interactor 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Plasma membranes, RIN1 and IDBG-58865 and ENSG00000174791 and 9610, RIN1 and IDBG-644375 and ENSBTAG00000017681 and 509295, Ras GTPase binding, Rin1 and IDBG-130658 and ENSMUSG00000024883 and 225870, this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0007613 and memory and biological process this GO :0008306 and associative learning and biological process this GO :0017016 and Ras GTPase binding and molecular function this GO :0030425 and dendrite and cellular component this GO :0031914 and negative regulation of synaptic plasticity and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043547 and positive regulation of GTPase activity and biological process, this GO :0005096: GTPase activator activity, this GO :0005096: GTPase activator activity and also this GO :0005515: protein binding and also this GO :0017016: Ras GTPase binding, this GO :0005515: protein binding, this GO :0017016: Ras GTPase binding, Ras and Rab interactor 1 |
| Identity | 18749 |
| Gene | RIN1 |
| Long gene name | Ras and Rab interactor 1 |
| Locus | 11q13, 2 |
| Discovery year | 2002-09-11 |
| GenBank acession | L36463 |
| Entrez gene record | 9610 |
| Pubmed identfication | 9144171 1849280 |
| RefSeq identity | NM_004292 |
| Classification | VPS9 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000167085 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue