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RIPK3 Antibody

RIPK3 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenRIPK3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Western blot: 1:1000
NotesTitration of the RIPK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis RIPK3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9Y572
PurityAntigen affinity
Description It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, The encoded protein is predominantly localized to the cytoplasm, and can induce apoptosis and weakly activate the NF-kappaB transcription factor, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals, and contains a C-terminal domain unique from other RIP family members, The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases
ImmunogenA portion of amino acids 480-509 from the human protein was used as the immunogen for this RIPK3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the RIPK3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetRIPK3
Short nameRIPK3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namereceptor-interacting serine-threonine kinase 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Plasma membranes, RIP3, RIPK3 and IDBG-3902 and ENSG00000129465 and 11035, RIPK3 and IDBG-645676 and ENSBTAG00000018422 and 100850132, Ripk3 and IDBG-165974 and ENSMUSG00000022221 and 56532, alpha-beta cytotoxic T cell extravasation and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0001914 and regulation of T cell mediated cytotoxicity and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0002819 and regulation of adaptive immune response and biological process this GO :0003713 and transcription coactivator activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004704 and NF-kappaB-inducing kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0010922 and positive regulation of phosphatase activity and biological process this GO :0016772 and transferase activity, this GO :0003713: transcription coactivator activity, this GO :0003713: transcription coactivator activity and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004704: NF-kappaB-inducing kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004704: NF-kappaB-inducing kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0032403: protein complex binding, this GO :0042802: identical protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0032403: protein complex binding and also this GO :0042802: identical protein binding, transferring phosphorus-containing groups and molecular function this GO :0032147 and activation of protein kinase activity and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032649 and regulation of interferon-gamma production and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038061 and NIK/NF-kappaB signaling and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043029 and T cell homeostasis and biological process this GO :0045087 and innate immune response and biological process this GO :0046006 and regulation of activated T cell proliferation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048535 and lymph node development and biological process this GO :0048536 and spleen development and biological process this GO :0048538 and thymus development and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051347 and positive regulation of transferase activity and biological process this GO :0051351 and positive regulation of ligase activity and biological process this GO :0051353 and positive regulation of oxidoreductase activity and biological process this GO :0060545 and positive regulation of necroptotic process and biological process this GO :0070235 and regulation of activation-induced cell death of T cells and biological process this GO :0070266 and necroptotic process and biological process this GO :0090312 and positive regulation of protein deacetylation and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097342 and ripoptosome and cellular component this GO :1990000 and amyloid fibril formation and biological process this GO :2000377 and regulation of reactive oxygen species metabolic process and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2000452 and regulation of CD8-positive, 507427, receptor-interacting serine-threonine kinase 3
Identity 10021
Gene RIPK3
Long gene name receptor interacting serine/threonine kinase 3
Synonyms gene name receptor-interacting serine-threonine kinase 3
Synonyms RIP3
Locus 14q12
Discovery year 1999-12-17
GenBank acession AF156884
Entrez gene record 11035
Pubmed identfication 10339433 10358032
RefSeq identity NM_006871
Havana BLAST/BLAT OTTHUMG00000029349

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