Name : RIPK3 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN1888342662
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | RIPK3 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC, WB |
| Recommended dilutions | IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the RIPK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This RIPK3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9Y572 |
| Purity | Antigen affinity |
| Description | It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, The encoded protein is predominantly localized to the cytoplasm, and can induce apoptosis and weakly activate the NF-kappaB transcription factor, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals, and contains a C-terminal domain unique from other RIP family members, The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases |
| Immunogen | A portion of amino acids 480-509 from the human protein was used as the immunogen for this RIPK3 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the RIPK3 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | RIPK3 |
| Short name | RIPK3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | receptor-interacting serine-threonine kinase 3 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Plasma membranes, RIP3, RIPK3 and IDBG-3902 and ENSG00000129465 and 11035, RIPK3 and IDBG-645676 and ENSBTAG00000018422 and 100850132, Ripk3 and IDBG-165974 and ENSMUSG00000022221 and 56532, alpha-beta cytotoxic T cell extravasation and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0001914 and regulation of T cell mediated cytotoxicity and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0002819 and regulation of adaptive immune response and biological process this GO :0003713 and transcription coactivator activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004704 and NF-kappaB-inducing kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0010922 and positive regulation of phosphatase activity and biological process this GO :0016772 and transferase activity, this GO :0003713: transcription coactivator activity, this GO :0003713: transcription coactivator activity and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004704: NF-kappaB-inducing kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004704: NF-kappaB-inducing kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0032403: protein complex binding, this GO :0042802: identical protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0032403: protein complex binding and also this GO :0042802: identical protein binding, transferring phosphorus-containing groups and molecular function this GO :0032147 and activation of protein kinase activity and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032649 and regulation of interferon-gamma production and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038061 and NIK/NF-kappaB signaling and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043029 and T cell homeostasis and biological process this GO :0045087 and innate immune response and biological process this GO :0046006 and regulation of activated T cell proliferation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048535 and lymph node development and biological process this GO :0048536 and spleen development and biological process this GO :0048538 and thymus development and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051347 and positive regulation of transferase activity and biological process this GO :0051351 and positive regulation of ligase activity and biological process this GO :0051353 and positive regulation of oxidoreductase activity and biological process this GO :0060545 and positive regulation of necroptotic process and biological process this GO :0070235 and regulation of activation-induced cell death of T cells and biological process this GO :0070266 and necroptotic process and biological process this GO :0090312 and positive regulation of protein deacetylation and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097342 and ripoptosome and cellular component this GO :1990000 and amyloid fibril formation and biological process this GO :2000377 and regulation of reactive oxygen species metabolic process and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2000452 and regulation of CD8-positive, 507427, receptor-interacting serine-threonine kinase 3 |
| Identity | 10021 |
| Gene | RIPK3 |
| Long gene name | receptor interacting serine/threonine kinase 3 |
| Synonyms gene name | receptor-interacting serine-threonine kinase 3 |
| Synonyms | RIP3 |
| Locus | 14q12 |
| Discovery year | 1999-12-17 |
| GenBank acession | AF156884 |
| Entrez gene record | 11035 |
| Pubmed identfication | 10339433 10358032 |
| RefSeq identity | NM_006871 |
| Havana BLAST/BLAT | OTTHUMG00000029349 |