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RNA polymerase II Antibody

RNA polymerase II Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRNA polymerase II Primary Polyclonal Antibody
Also known asRNA polymerase II PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRNA polymerase II
SpecificityThis is a highly specific antibody against RNA polymerase II
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Pol II/RNA polymerase II
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additionally, Although Pol II function requires the cooperation of all twelve subunits, The largest subunit of Pol II (referred to as RPB1 or RPB205) is a 1, Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, Without proper function of the large subunit, a groove that is necessary for transcription of the DNA template, forms the active center of the Pol II enzyme, mRNA synthesis and subsequent transcription elongation cannot occur, the large subunit participates in forming the DNA-binding domain of Pol II, the largest subunit conveys Pol II catalytic activity and, thereby allowing transcription to begin, together with the second largest subunit, 840 amino acid protein that contains one C2H2-type zinc finger and a C-terminal domain comprised of several heptapeptide repeats, RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DNA directed RNA polymerase II A, DNA-directed RNA polymerase II largest subunit, DNA-directed RNA polymerase II subunit A, POLR2, RPB1_HUMAN, POLR2A
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRNA polymerase II
Short nameRNA polymerase II Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRNA polymerizing enzyme II (Antibody to)
Alternative techniqueantibodies
Identity 9191
Gene POLR2D
Long gene name RNA polymerase II subunit D
Synonyms gene name polymerase (RNA) II (DNA directed) polypeptide D
Synonyms RBP4
Synonyms name RNA polymerase II subunit hsRBP4
Locus 2q14, 3
Discovery year 1993-12-07
GenBank acession U85510
Entrez gene record 5433
Pubmed identfication 9528765
RefSeq identity NM_004805
Classification RNA polymerase subunits
Havana BLAST/BLAT OTTHUMG00000131531

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