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RNF126 Antibody, ALEXA FLUOR 488

RNF126 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, RNF126 Polyclonal Antibody
Also known asAnti-RNF126 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRNF126
SpecificityThis is a highly specific antibody against RNF126
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range80-130/313
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF126
Gene ID Number55658
Swiss ProtQ9BV68
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen By ubiquitinating CDKN1A/p21 and targeting it for degradation, Depending on the associated E2 ligase, FLT3, MET and CXCR4, May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome, May also play a role in the endosomal recycling of IGF2R, May monoubiquitinate AICDA (PubMed:23277564), May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174), Through their polyubiquitination, may also promote cell proliferation (PubMed:23026136), may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates, the cation-independent mannose-6-phosphate receptor (PubMed:24275455), E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms FLJ20552
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the RNF126 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetRNF126
Short nameRNF126 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, RNF126 (Antibody to)
Alternative techniqueantibodies
Identity 21151
Gene RNF126
Long gene name ring finger protein 126
Locus 19p13, 3
Discovery year 2003-05-21
GenBank acession BC025374
Entrez gene record 55658
RefSeq identity NM_017876
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000180592

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