Name : RNF2 Antibody / RING1B
Supplier : NJS POLY
Price :406
SKU : GEN8704888624
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | RNF2 / RING1B |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the RNF2 antibody should be determined by the researcher |
| Intented use | This RNF2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q99496 |
| Purity | Antigen affinity |
| Description | It has been shown to interact with, Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation, Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, The protein encoded by this gene is one of the PcG proteins, This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity, and suppress the activity of, as well as in cell proliferation in early development, transcription factor CP2 (TFCP2/CP2), E3 ubiquitin-protein ligase RING2/RING1B is an enzyme that in humans is encoded by the RNF2 gene |
| Immunogen | Amino acids DHLSKYLAVRLALEELRSKGESNQMNLDTASEKQ of human RNF2 were used as the immunogen for the RNF2 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RNF2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | Nuclear |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | RNF2 / RING1B |
| Short name | RNF2 Antibody / RING1B |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | RNF2 (Antibody to) / RING1B |
| Alternative technique | antibodies |
| Identity | 10061 |
| Gene | RNF2 |
| Long gene name | ring finger protein 2 |
| Synonyms | BAP-1 BAP1 DING HIPI3 RING1B RING2 |
| Locus | 1q25, 3 |
| Discovery year | 1997-06-09 |
| GenBank acession | BC012583 Y10571 |
| Entrez gene record | 6045 |
| Pubmed identfication | 11513855 |
| RefSeq identity | NM_007212 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000035391 |