Name : ROR beta Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2804085040
| Long name | ROR beta Primary Polyclonal Antibody |
| Also known as | ROR beta PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ROR beta |
| Specificity | This is a highly specific antibody against ROR beta |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 390-440/470 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RORB |
| Gene ID number | 6096 |
| Swiss Prot | Q92753 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Considered to have intrinsic transcriptional activity, In cone photoreceptor cells, Involved in the regulation of the period length and stability of the circadian rhythm, May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons, May control cytoarchitectural patterning of neocortical neurons during development, May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity), Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway, Required for normal postnatal development of rod and cone photoreceptor cells, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity, regulates transcription of OPN1SW, Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Nuclear receptor ROR-beta, Nuclear receptor RZR beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, RAR related orphan receptor B, RAR related orphan receptor beta, ROR BETA, RORB_HUMAN, RZR BETA, RZRB, Retinoic acid binding receptor beta, Retinoid-related orphan receptor-beta, Rorb, NR1F2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ROR beta |
| Short name | ROR beta Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ROR b (Antibody to) |
| Alternative technique | antibodies |
| Identity | 43773 |
| Gene | LINC-ROR |
| Long gene name | long intergenic non-protein coding RNA, regulator of reprogramming |
| Synonyms | lincRNA-RoR lincRNA-ST8SIA3 ROR |
| Locus | 18q21, 31 |
| Discovery year | 2012-05-01 |
| GenBank acession | HQ315778 |
| Entrez gene record | 100885779 |
| Pubmed identfication | 21057500 23208419 23541921 23597480 24463816 |
| RefSeq identity | NR_048536 |
| Classification | Long non-coding RNAs Competing endogenous long non-coding RNAs |
| Havana BLAST/BLAT | OTTHUMG00000171587 |