Filters

ROS1 Antibody

ROS1 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenROS1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the ROS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis ROS1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P08922
PurityAntigen affinity
Description IRS1 and PLCG2, MAPK1, MAPK3, May activate other downstream signaling proteins including AKT1, May activate several downstream signaling pathways related to cell differentiation, May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth, Mediates the phosphorylation and the activation of VAV3, Mediates the phosphorylation of PTPN11, a guanine nucleotide exchange factor regulating cell morphology, an activator of this pathway, growth and survival including the PI3 kinase-mTOR signaling pathway, proliferation, Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium
ImmunogenThis ROS1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1744-1777 amino acids from the C-terminal region of human ROS1
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ROS1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetROS1
Short nameROS1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameROS1 (Antibody to)
Alternative techniqueantibodies
Identity 10261
Gene ROS1
Long gene name ROS proto-oncogene 1, receptor tyrosine kinase
Synonyms gene name receptor tyrosine kinase , v-ros avian UR2 sarcoma virus oncogene homolog 1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) c-ros oncogene 1
Synonyms MCF3 ROS c-ros-1
Locus 6q22, 1
Discovery year 1986-01-01
GenBank acession M13599
Entrez gene record 6098
Pubmed identfication 1611909
Classification Fibronectin type III domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000016188
Locus Specific Databases LRG_997

Subscribe to our Newsletter