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RSPO3 Antibody / R-spondin 3

RSPO3 Antibody / R-spondin 3 size: 0.05 ml 199

Supplier NJS POLY
Price 199
Size 0.05 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenRSPO3 / R-spondin 3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutionsWestern blot: 1:1000-2000
Intented useThis RSPO3 antibodyis to be used only for research purposes and not for diagnostics
Gene ID #84870
Uniprot #Q9BXY4
PurityAntigen affinity
Description Acts as a ligand for frizzled FZD8 and LRP6, Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, LGR5 or LGR6), May negatively regulate the TGF-beta pathway, Upon binding to LGR4-6 (LGR4, an important regulator of the Wnt signaling pathway, triggering the canonical Wnt signaling pathway to increase expression of target genes, R-spondin-3 is an activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors
ImmunogenA portion of amino acids 214-248 from the human protein was used as the immunogen for the RSPO3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the RSPO3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetRSPO3 / R-spondin 3
Short nameRSPO3 Antibody / R-spondin 3
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRSPO3 (Antibody to) / R-spondin 3
Alternative techniqueantibodies
Identity 20866
Gene RSPO3
Long gene name R-spondin 3
Synonyms gene THSD2
Synonyms gene name domain containing 2 R-spondin 3 homolog (Xenopus laevis) , thrombospondin, type I
Synonyms FLJ14440
Locus 6q22, 33
Discovery year 2003-04-29
GenBank acession BC022367
Entrez gene record 84870
Pubmed identfication 10842357 15469841
RefSeq identity NM_032784
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000015521

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