Name : RUNX3(Ser338) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN4169247931
| Long name | RUNX3(Ser338) Primary Polyclonal Antibody |
| Also known as | RUNX3(Ser338) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | RUNX3 Ser338 |
| Specificity | This is a highly specific antibody against RUNX3 Ser338 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser338 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human RUNX3 around the phosphorylation site of Ser338 |
| Gene ID number | 864 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Heterodimer of an alpha and a beta subunit, Interacts with TLE1 and SUV39H1, May be involved in the control of cellular proliferation and/or differentiation (By similarity), Subcellular location in Nucleus, The alpha subunit binds DNA as a monomer and through the Runt domain, and also to the enhancers of the T-cell receptor genes, the core sequences in the enhancer of the polyomavirus, DNA-binding is increased by heterodimerization, RUNX3 binds to the core site of murine Leukemia virus |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Acute myeloid leukemia 2 protein, Acute myeloid leukemia 2 protein, CBF-alpha 3, CBF-alpha 3, Core-binding factor, Core-binding factor, Oncogene AML-2, OncogeneAML-2, PEA2-alpha C, PEA2-alpha C, PEBP2-alpha C, PEBP2-alpha C, Polyomavirus enhancer-binding protein 2 alpha C subunit, Polyomavirus enhancer-binding protein 2 alpha C subunit, RUNX 3, RUNX-3, RUNX3_HUMAN, Runt-related transcription factor 3, SL3-3 enhancer factor 1 alpha C subunit, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit, SL3/AKV core-binding factor alpha C subunit, alpha 3 subunit, alpha 3 subunit, p-RUNX3Ser338 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RUNX3(Ser338) |
| Short name | RUNX3(Ser338) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | runt-related transcription factor 3(Ser338) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | AML2 and CBFA3 and PEBP2aC, ATP binding, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007411 and axon guidance and biological process this GO :0031069 and hair follicle morphogenesis and biological process this GO :0031175 and neuron projection development and biological process this GO :0032609 and interferon-gamma production and biological process this GO :0045087 and innate immune response and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0048469 and cell maturation and biological process this GO :0048935 and peripheral nervous system neuron development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, RUNX3 and IDBG-645327 and ENSBTAG00000019800 and 617389, RUNX3 and IDBG-94257 and ENSG00000020633 and 864, Runx3 and IDBG-196773 and ENSMUSG00000070691 and 12399, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0002062 and chondrocyte differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006355 and regulation of transcription, this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, runt-related transcription factor 3 |
| Identity | 10473 |
| Gene | RUNX3 |
| Long gene name | runt related transcription factor 3 |
| Synonyms gene | CBFA3 |
| Synonyms gene name | runt-related transcription factor 3 |
| Synonyms | AML2 PEBP2A3 |
| Locus | 1p36, 11 |
| Discovery year | 1994-11-02 |
| GenBank acession | BC013362 |
| Entrez gene record | 864 |
| Pubmed identfication | 7835892 |
| RefSeq identity | NM_004350 |
| Havana BLAST/BLAT | OTTHUMG00000003316 |