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SAMHD1 Antibody, ALEXA FLUOR 488

SAMHD1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, SAMHD1 Polyclonal Antibody
Also known asAnti-SAMHD1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSAMHD1
SpecificityThis is a highly specific antibody against SAMHD1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SAMHD1
Gene ID Number4861
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A form of Aicardi-Goutieres syndrome, Clinical features as thrombocytopenia, Death often occurs in early childhood, May play a role in mediating proinflammatory responses to TNF-alpha signaling, No expression is seen in brain and thymus, Severe neurological dysfunctions manifest in infancy as progressive microcephaly, a genetically heterogeneous disease characterized by cerebral atrophy, and negative serologic investigations for common prenatal infection, chronic cerebrospinal fluid (CSF) lymphocytosis, dystonic posturing and profound psychomotor retardation, hepatosplenomegaly and elevated hepatic transaminases along with intermittent fever may erroneously suggest an infective process, increased CSF alpha-interferon, intracranial calcifications, leukoencephalopathy, liver, lung and peripheral blood leukocytes, placenta, skeletal muscle, small intestine, spasticity, spleen, Involvement in disease:Defects in SAMHD1 are the cause of Aicardi-Goutieres syndrome type 5 (AGS5) , Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response, Tissue specificity:Expressed in heart
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms SBBI88 Mg11 HDDC1 MOP-5 AGS5
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the SAMHD1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetSAMHD1
Short nameSAMHD1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, SAMHD1 (Antibody to)
Alternative techniqueantibodies
Identity 15925
Gene SAMHD1
Long gene name SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
Synonyms gene name SAM domain and HD domain 1
Synonyms name HD domain containing 1 monocyte protein 5 Aicardi-Goutieres syndrome 5
Locus 20q11, 23
Discovery year 2001-07-31
GenBank acession AF228421
Entrez gene record 25939
Pubmed identfication 11064105 11230166 22056990
RefSeq identity NM_015474
Classification Sterile alpha motif domain containing
Havana BLAST/BLAT OTTHUMG00000032402
Locus Specific Databases LRG_281

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