Name : SASS6 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9049305314
| Long name | Biotin Conjugated, SASS6 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SASS6 |
| Specificity | This is a highly specific antibody against SASS6 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human SASS6 |
| Gene ID number | 163786 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6, Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole, LK4, SAS-6, SAS-6 associates only transiently with nascent procentrioles, SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain, SAS-6 is necessary for procentriole formation in human cell lines and is localized asymmetrically next to the centriole at the onset of procentriole formation, SAS-6 levels oscillate during the cell cycle, The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation, and it accumulates again at the end of the following G1 phase, it is degraded in mitosis starting at anaphase, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles, SAS-6 (spindle assembly abnormal protein 6 homolog |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | DKFZp761A078 SAS-6 FLJ22097 SAS6 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SASS6 Conjugated |
| Short name | Conjugated, SASS6 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, SASS6 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25403 |
| Gene | SASS6 |
| Long gene name | SAS-6 centriolar assembly protein |
| Synonyms gene name | elegans) , spindle assembly 6 homolog (C |
| Locus | 1p21, 2 |
| Discovery year | 2005-10-13 |
| GenBank acession | AL834265 |
| Entrez gene record | 163786 |
| Pubmed identfication | 15665853 14654843 |
| RefSeq identity | NM_194292 |
| Havana BLAST/BLAT | OTTHUMG00000010754 |