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Separase (Ser1073) Antibody, ALEXA FLUOR 594

Separase (Ser1073) Antibody, ALEXA FLUOR 594 size: 100ul 350

Price 350
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, Separase (Ser1073) Polyclonal Antibody
Also known asAnti-Separase Ser1073 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSeparase Ser1073
SpecificityThis is a highly specific antibody against Separase Ser1073
ModificationPhosphorylation
Modification SiteSer1073
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human ESPL1 around the phosphorylation site of Ser1073
Gene ID Number9700
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen As the cellular division process continues, Cohesin plays an important role in cohering sister chromatids during the prophase through anaphase stages of mitosis, Each cell must receive one chromatid of every chromosome, It not only cleaves cohesin at the onset of anaphase but also cleaves itself, Separase activity is highly regulated, Should a human cell become an aneuploid (one too many or too few chromatids), Should the embryo survive, allowing the chromatids to separate and divide with the cell, during mitosis, it will most likely develop severe birth defects or later develop malignant cancers, making certain that genomic information is replicated accurately, promoting downregulation of separase after anaphase, separase destroys cohesin by means of cleavage, the embryo most likely will not survive, Separase is a cysteine protease that is essential for mitotic progression by separating sister chromatids
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms ESP 1, ESP-1, ESP1, ESPL 1, ESPL-1, ESPL1, ESPL1_HUMAN, Extra spindle poles like 1, Extra spindle poles like 1 protein, SSE, Separase, Separin, Similar to fission yeast cut1and gene, Caspase like protein ESPL1
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetSeparase (Ser1073)
Short nameSeparase (Ser1073) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Separase (Ser1073) (Antibody to)
Alternative techniqueantibodies

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