| Alternative name1 | A170, EBI3-associated Protein of 60kD, EBIAP, ORCA, OSIL, Oxidative Stress Induced-like, PDB3, Paget Disease of Bone 3, Phosphotyrosine-independent Ligan, Phosphotyrosine-independent Ligand for the Lck SH2 Domain of 62kD, p60, p62B, Anti-Sequestosome 1 (SQSTM1 |
| Alternative name2 | A170, EBI3-associated Protein of 60kD, EBIAP, ORCA, OSIL, Oxidative Stress Induced-like, PDB3, Paget Disease of Bone 3, Phosphotyrosine-independent Ligan, Phosphotyrosine-independent Ligand for the Lck SH2 Domain of 62kD, p60, p62B, Sequestosome 1 (SQSTM1 |
| Alternative name3 | A170, EBI3-associated Protein of 60kD, EBIAP, ORCA, OSIL, Oxidative Stress Induced-like, PDB3, Paget Disease of Bone 3, Phosphotyrosine-independent Ligan, Phosphotyrosine-independent Ligand for the Lck SH2 Domain of 62kD, p60, p62B, Sequestosome 1 (SQSTM1 |
| Alternative name4 | Sequestosome 1 |
| Alternative name5 | A170, EBI3-associated Protein of 60kD, EBIAP, ORCA, OSIL, Oxidative Stress Induced-like, PDB3, Paget Disease of Bone 3, Phosphotyrosine-independent Ligan, Phosphotyrosine-independent Ligand for the Lck SH2 Domain of 62kD, p60, p62B, Anti -Sequestosome 1 (SQSTM1 |
| Other names | EBI3-associated protein of 60 kDa, EBI3-associated protein of 60 kDa, EBI3-associated protein p60, EBIAP, EBIAP, OTTHUMP00000198118, OTTHUMP00000198119, OTTHUMP00000223467, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Sequestosome-1, Ubiquitin-binding protein p62, oxidative stress induced like, p60, phosphotyrosine independent ligand for the Lck SH2 domain p62, phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, sequestosome 1, sequestosome-1, ubiquitin-binding protein p62, Sequestosome 1 |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | A170, ORCA, OSIL, OSIL, PDB3, SQSTM1, ZIP3, p60, p62, p62B, SQSTM1 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Mouse, Rat, Bovine |
| Specificity and cross-reactivity | See the immunogen field also, rat and bovine, Species Crossreactivity: This antibody is expected to recognize p60 in mouse |
| Purification method | Serum |
| Form/Appearance | Centrifuge to remove any insoluble material, Reconstitute in 100ul of sterile water, Supplied as a lyophilized powder |
| Concentration | N/A |
| Storage and shipping | For maximum recovery of product, Further dilutions can be made in assay buffer, Reconstitute to nominal volume by adding sterile 40-50% glycerol and For optimal long term storage, Reconstituted product is stable for 3 months productone should be stored at -20 degrees Celsius, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Lyophilized powder Store at 4 degrees Celsius for short term storage |
| Tested for: | N/A |
| Description | FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling, Receptor agonists are often tested for drug development, factors or kinases, increase , (an , Induced protein genes, at , enzyme , genetic transcription, level , of , of , or , other , production , protein) , the , the  |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | A170, EBI3-associated Protein of 60kD, EBIAP, ORCA, OSIL, Oxidative Stress like, PDB3, Paget Disease of Bone 3, Phosphotyrosine-independent Ligan, Phosphotyrosine-independent Ligand for the Lck SH2 Domain of 62kD, p60, p62B, Sequestosome 1 (SQSTM1 |
| Short name | A170, EBI3-associated Protein of 60kD, EBIAP, ORCA, OSIL, Oxidative Stress -like, PDB3, Paget Disease of Bone 3, Phosphotyrosine-independent Ligan Antibody, Phosphotyrosine-independent Ligand for the Lck SH2 Domain of 62kD, p60, p62B, Sequestosome 1 (SQSTM1 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | A170, EBIAP, Epstein-Barr virus induced 3-associated Protein on 60kD, ORCA, OSIL, Oxidative Stress Induced-like, PDB3, Paget Disease on Bone 3, Phosphotyrosine-independent Ligan (Antibody to), Phosphotyrosine-independent Ligand to measure the lymphocyte-specific protein tyrosine kinase SH2 Domain on 62kD, p60, p62B, Sequestosome 1 (sequestosome 1 |
| Alternative technique | antibodies |
| Alternative to gene target | A170 and OSIL and p60 and p62 and p62B and PDB3 and ZIP3, BT, EBI3 and IDBG-18580 and ENSG00000105246 and 10148, EBI3 and IDBG-644295 and ENSBTAG00000012829 and 514933, Ebi3 and IDBG-191286 and ENSMUSG00000003206 and 50498, Extracellular, IL-27B and IL27B, K63-linked polyubiquitin binding, SQSTM1 and IDBG-61811 and ENSG00000161011 and 8878, Sqstm1 and IDBG-168358 and ENSMUSG00000015837 and 18412, interleukin-27 receptor binding, nuclei, sequestosome 1, this GO :0000407 and pre-autopha this GO somal structure and cellular component this GO :0000932 and cytoplasmic mRNA processing body and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002376 and immune system process and biological process this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005776 and autophagic vacuole and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006914 and autophagy and biological process this GO :0006950 and response to stress and biological process this GO :0008104 and protein localization and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016197 and endosomal transport and biological process this GO :0016234 and inclusion body and cellular component this GO :0016235 and aggresome and cellular component this GO :0016236 and macroautophagy and biological process this GO :0016239 and positive regulation of macroautophagy and biological process this GO :0016605 and PML body and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030154 and cell differentiation and biological process this GO :0030971 and receptor tyrosine kinase binding and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043122 and regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046578 and regulation of Ras protein signal transduction and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070530 and K63-linked polyubiquitin binding and molecular function this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004674: protein serine/threonine kinase activity, this GO :0004674: protein serine/threonine kinase activity and also this GO :0005080: protein kinase C binding and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019901: protein kinase binding and also this GO :0030971: receptor tyrosine kinase binding and also this GO :0042169: SH2 domain binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0043130: ubiquitin binding and also this GO :0070530: K63-linked polyubiquitin binding, this GO :0004896 and cytokine receptor activity and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006959 and humoral immune response and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0042088 and T-helper 1 type immune response and biological process this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045523 and interleukin-27 receptor binding and molecular function this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process, this GO :0004896: cytokine receptor activity, this GO :0004896: cytokine receptor activity and also this GO :0005125: cytokine activity and also this GO :0005515: protein binding and also this GO :0045523: interleukin-27 receptor binding, this GO :0005080: protein kinase C binding, this GO :0005125: cytokine activity, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0019901: protein kinase binding, this GO :0030971: receptor tyrosine kinase binding, this GO :0042169: SH2 domain binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0043130: ubiquitin binding, this GO :0045523: interleukin-27 receptor binding, this GO :0070530: K63-linked polyubiquitin binding, 105440 and IDBG-640935 and ENSBTAG00000015591 and 338045, Epstein-Barr virus induced 3 |
| Identity | 11280 |
| Gene | SQSTM1 |
| Long gene name | sequestosome 1 |
| Synonyms gene | PDB3 OSIL |
| Synonyms gene name | Paget disease of bone 3 oxidative stress induced like |
| Synonyms | p62 p60 p62B A170 |
| Locus | 5q35, 3 |
| Discovery year | 2000-06-13 |
| GenBank acession | U46751 |
| Entrez gene record | 8878 |
| Pubmed identfication | 8650207 8551575 |
| Classification | Zinc fingers ZZ-type |
| Havana BLAST/BLAT | OTTHUMG00000150643 |