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SERCA2 ATPase Antibody

SERCA2 ATPase Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSERCA2 ATPase
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the SERCA2 ATPase antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis SERCA2 ATPase antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P16615
PurityAntigen affinity
Description ATP2B, Expression was also observed in the infundibulum and outer root sheath of hair follicles, In Darier disease skin, Perilesional Darier disease skin was comparable to normal skin, SERCA2 belongs to the large family of P-type cation pumps that couple ATP hydrolysis with cation transport across membranes, SERCA2 was expressed in all specimens, The gene is mapped on 12q24, There was variable suprabasal expression, They are closely related to the plasma membrane Ca(2+)-ATPases, also called ATP2A2, and acantholytic lesional cells, and arrector pili muscle, apocrine gland cells, encodes one of the SERCA Ca(2+)-ATPases, germinative and mature cells of sebaceous glands, or PMCAs, secretory coil and duct of eccrine glands, strong SERCA2 positivity was detected in the basal, suprabasal, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells, with pronounced expression in the subnuclear aspect of basal epidermal keratinocytes, 11, Sarcoplasmic reticulum Ca(2+)-ATPase 2
Immunogen mouse and rat), An amino acid sequence from the middle region of human SERCA2 ATPase (QRDACLNARCFARVE) was used as the immunogen for this SERCA2 ATPase antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SERCA2 ATPase antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSERCA2 ATPase
Short nameSERCA2 ATPase Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSERCA2 ATPase (Antibody to)
Alternative techniqueantibodies
Identity 812
Gene ATP2A2
Long gene name ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
Synonyms gene ATP2B DAR
Synonyms gene name ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Synonyms SERCA2
Synonyms name sarcoplasmic/endoplasmic reticulum calcium ATPase 2 calcium pump 2
Locus 12q24, 11
Discovery year 1990-09-10
Entrez gene record 488
Pubmed identfication 10080178
RefSeq identity NM_001681
Classification ATPases Ca2+ transporting
Havana BLAST/BLAT OTTHUMG00000169327

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