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SHANK2 Antibody

SHANK2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSHANK2 Primary Polyclonal Antibody
Also known asSHANK2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSHANK2
SpecificityThis is a highly specific antibody against SHANK2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHANK2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, Shank recruits betaPIX and PAK to spines to regulate postsynaptic structure and interacts with NMDA receptor and metabotropic glutamate receptor complexes, The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s), The PSD is an electron-dense structure underneath the postsynaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the presynaptic neurotransmitter release site, Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development, and cell adhesion molecules, receptors, signaling enzymes, SH3 and multiple ankyrin repeat domains 1-3 (Shank1-3) of the Shank/ProSAP family are molecular scaffolds in the postsynaptic density (PSD)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CTTNBP1, CortBP1, Cortactin SH3 domain-binding protein, Cortactin-binding protein 1, GKAP/SAPAP interacting protein, GKAP/SAPAP-interacting protein, KIAA1022, PROSAP1, Proline rich synapse associated protein 1, Proline-rich synapse-associated protein 1, SH3 and multiple ankyrin repeat domains protein 2, SHAN2_HUMAN, SHANK, SPANK-3, SPANK3, Shank2, Shank2, Cortactin binding protein 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSHANK2
Short nameSHANK2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSHANK2 (Antibody to)
Alternative techniqueantibodies
Identity 14295
Gene SHANK2
Long gene name SH3 and multiple ankyrin repeat domains 2
Synonyms gene CORTBP1
Synonyms gene name cortactin binding protein 1
Synonyms CTTNBP1 ProSAP1 SHANK SPANK-3
Locus 11q13, 3-q13, 4
Discovery year 2002-02-22
GenBank acession AF141901
Entrez gene record 22941
Pubmed identfication 10506216
RefSeq identity NM_012309
Classification Ankyrin repeat domain containing Sterile alpha motif domain containing PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000154615

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