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SHOC2 Antibody, Biotin Conjugated

SHOC2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SHOC2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSHOC2
SpecificityThis is a highly specific antibody against SHOC2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SHOC2/Sur8
Gene ID number8036
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Affected subjects also have easily pluckable, NSLAH children display macrocephaly, Upon M-Ras/MRAS activation, high forehead, hypertelorism, low-set and posteriorly rotated ears, palpebral ptosis, short and webbed neck and pectus anomalies, sparse, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes, thin and slow-growing hair, Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) , Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms KIAA0862 SOC2 SUR-8 SOC-2 SUR8
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSHOC2 Conjugated
Short name Conjugated, SHOC2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SHOC2 (Antibody to)
Alternative techniqueantibodies
Identity 15454
Gene SHOC2
Long gene name SHOC2, leucine rich repeat scaffold protein
Synonyms gene name C, elegans) SHOC2 leucine-rich repeat scaffold protein , soc-2 (suppressor of clear, elegans) homolog soc-2 suppressor of clear homolog (C
Locus 10q25, 2
Discovery year 2001-03-30
GenBank acession AB020669
Entrez gene record 8036
Pubmed identfication 9618511 9674433 10783161
RefSeq identity NM_007373
Havana BLAST/BLAT OTTHUMG00000019047
Locus Specific Databases LRG_753

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