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Slc26a5 Antibody

Slc26a5 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSlc26a5 Primary Polyclonal Antibody
Also known asSlc26a5 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSlc26a5
SpecificityThis is a highly specific antibody against Slc26a5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Slc26a5
Gene ID number375611
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen It acts as a motor protein that converts auditory stimuli to length changes in outer hair cells, It acts as an incomplete transporter since it moves anions across the membrane, It is a bidirectional voltage-to-force converter which uses cytoplasmic anions as extrinsic voltage sensors, Mutations in SLC26A5 have been associated with non-syndromic hearing loss, Salicylate, The anions are translocated across the membrane in response to changes in the transmembrane voltage, The area decreases when the anion is near the cytoplasmic face of the membrane (short state), They move towards the extracellular surface following hyperpolarization, This translocation triggers conformational changes in the protein that alter its surface area in the plane of the plasma membrane, acts as competitive antagonist at the anion-binding site, an inhibitor of outer hair cell motility, and increases when the ion has crossed the membrane to the outer surface (long state), and towards the cytoplasmic side in response to depolarization, but does not allow the anions to dissociate and escape to the extracellular space, member 5) is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing, SLC26A5 (Solute carrier family 26
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DFNB 61, DFNB61, Deafness neurosensory autosomal recessive 61, MGC118886, MGC118887, MGC118888, MGC118889, PRES, Prestin, Prestin motor protein, S26A5_HUMAN, SLC26A5, Solute carrier family 26 member 5, Solute carrier family 26 member 5 prestin, Prestin
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSlc26a5
Short nameSlc26a5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSlc26a5 (Antibody to)
Alternative techniqueantibodies
Identity 9359
Gene SLC26A5
Long gene name solute carrier family 26 member 5
Synonyms gene PRES
Synonyms gene name member 5 , prestin (motor protein) solute carrier family 26 (anion exchanger)
Synonyms DFNB61
Synonyms name 61 , autosomal recessive, deafness, neurosensory
Locus 7q22, 1
Discovery year 2000-06-08
GenBank acession AC005064
Entrez gene record 375611
Pubmed identfication 10821263
RefSeq identity NM_198999
Classification Solute carriers Deafness associated genes
Havana BLAST/BLAT OTTHUMG00000149911

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