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SLC26A6 Antibody , ALEXA FLUOR 488

SLC26A6 Antibody , ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, SLC26A6 Polyclonal Antibody
Also known asAnti-SLC26A6 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSLC26A6
SpecificityThis is a highly specific antibody against SLC26A6
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range438-484/759
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC26A6
Gene ID Number65010
Swiss ProtQ9BXS9
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as a versatile DIDS-sensitive inorganic and organic anion transporter that mediates the uptake of monovalent anions like chloride, Apical membrane chloride-bicarbonate exchanger that mediates luminal chloride absorption and bicarbonate secretion by the small intestinal brush border membrane and contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption, Function in multiple exchange modes involving pairs of these anions, Isoform 4: Apical membrane chloride-bicarbonate exchanger, Its association with carbonic anhydrase CA2 forms a bicarbonate transport metabolon, Mediates also intestinal chloride absorption and oxalate secretion, Mediates also the transcellular sulfate absorption and oxalate secretion across the apical membrane in the duodenum and the formate ion efflux at the apical brush border of cells in the proximal tubules of kidney, Plays a role in sperm capacitation by increasing intracellular pH, The apical membrane chloride-bicarbonate exchanger provides also a major route for fluid and bicarbonate secretion into the proximal tubules of the kidney as well as into the proximal part of the interlobular pancreatic ductal tree, Transepithelial oxalate secretion, and hence will dilute and alkalinize protein-rich acinar secretion, bicarbonate, chloride-formate, chloride-oxalate, chloride-oxalate and chloride-bicarbonate transport activities in the duodenum are inhibited by PKC activation in a calcium-independent manner, formate and hydroxyl ion and divalent anions like sulfate and oxalate, hence maximizes the local concentration of bicarbonate at the transporter site, oxalate-formate, oxalate-sulfate and chloride-formate exchange, possibly by providing a bicarbonate import pathway, thereby preventing hyperoxaluria and calcium oxalate urolithiasis, where it mediates electrogenic chloride-bicarbonate exchange with a chloride-bicarbonate stoichiometry of 1:2, which include chloride-bicarbonate, Apical membrane anion-exchanger with wide epithelial distribution that plays a role as a component of the pH buffering system for maintaining acid-base homeostasis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms DKFZp586E1422
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the SLC26A6 Antibody has a very high photo stability, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetSLC26A6
Short nameSLC26A6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, SLC26A6 (Antibody to)
Alternative techniqueantibodies
Identity 14472
Gene SLC26A6
Long gene name solute carrier family 26 member 6
Synonyms gene name member 6 , member 6 solute carrier family 26 (anion exchanger), solute carrier family 26
Synonyms name pendrin-like protein 1 pendrin L1 sulfate anion transporter anion transporter 1
Locus 3p21, 31
Discovery year 2001-01-25
GenBank acession AF279265
Entrez gene record 65010
Pubmed identfication 11087667 11247665
RefSeq identity NM_022911
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000186381

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