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SLC5A8 Antibody

SLC5A8 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSLC5A8 Primary Polyclonal Antibody
Also known asSLC5A8 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSLC5A8
SpecificityThis is a highly specific antibody against SLC5A8
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range301-336/610
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC5A8
Gene ID number160728
Swiss ProtQ8N695
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a tumor suppressor, Catalyzes passive carrier mediated diffusion of iodide, D-lactate, May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract, May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons, Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane, acetate, acetoacetate and alpha-ketoisocaproate), benzoate, including transport of monocarboxylates (short-chain fatty acids including L-lactate, lactate, mocarboxylate drugs (nicotinate, propionate, prostate cancer and glioma cell lines, pyruvate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, suppressing colony formation in colon cancer, valerate and butyrate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1, Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Apical iodide transporter, Electrogenic sodium monocarboxylate cotransporter, SLC5A8, SMCT, SMCT1, Sodium iodide-related cotransporter, Sodium-coupled monocarboxylate transporter 1, Solute carrier family 5 member 8, AIT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSLC5A8
Short nameSLC5A8 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 8 (Antibody to), solute carrier family 5 (iodide transporter)
Alternative techniqueantibodies
Alternative to gene target Plasma membranes, SLC5A8 and IDBG-547244 and ENSG00000256870 and 160728, SMCT1 and IDBG-636931 and ENSBTAG00000011525 and 615734, Slc5a8 and IDBG-183999 and ENSMUSG00000020062 and 216225, member 8, symporter activity, this GO :0005215 and transporter activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006810 and transport and biological process this GO :0006811 and ion transport and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0015293 and symporter activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005215: transporter activity, this GO :0005215: transporter activity and also this GO :0015293: symporter activity, this GO :0015293: symporter activity, solute carrier family 5 (iodide transporter)
Identity 19119
Gene SLC5A8
Long gene name solute carrier family 5 member 8
Synonyms gene name member 8 , member 8 solute carrier family 5 (sodium/monocarboxylate cotransporter), solute carrier family 5 (iodide transporter)
Synonyms AIT
Locus 12q23, 1-q23, 2
Discovery year 2003-05-12
GenBank acession AY081220
Entrez gene record 160728
Pubmed identfication 12107270 12829793
RefSeq identity NM_145913
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000170499

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