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SOCS6 Antibody

SOCS6 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSOCS6
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Western blot: 1:1000
NotesTitration of the SOCS6 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis SOCS6 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O14544
PurityAntigen affinity
Description A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines, CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling, The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells, The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family, The protein encoded by this gene contains a SH2 domain and a CIS homolog domain
ImmunogenA portion of amino acids 40-69 from the human protein was used as the immunogen for this SOCS6 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SOCS6 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSOCS6
Short nameSOCS6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namesuppressor on cytokine signaling 6 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CIS-4 and CIS4 and HSPC060 and SOCS-4 and SOCS-6 and SOCS4 and SSI4 and STAI4 and STATI4, Cell surfaces, SOCS6 and IDBG-4847 and ENSG00000170677 and 9306, SOCS6 and IDBG-643512 and ENSBTAG00000017412 and 615146, Socs6 and IDBG-163115 and ENSMUSG00000056153 and 54607, protein binding, this GO :0001772 and immunological synapse and cellular component this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006952 and defense response and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0010498 and proteasomal protein catabolic process and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0040008 and regulation of growth and biological process this GO :0045087 and innate immune response and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, suppressor of cytokine signaling 6
Identity 16833
Gene SOCS6
Long gene name suppressor of cytokine signaling 6
Synonyms gene SOCS4
Synonyms gene name suppressor of cytokine signaling 4
Synonyms CIS4 SSI4 HSPC060 STATI4 STAI4 Cish4
Locus 18q22, 2
Discovery year 2002-11-13
GenBank acession AB006968
Entrez gene record 9306
Pubmed identfication 9344848 11042152
Classification Suppressors of cytokine signaling SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000132816

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