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SorLA Antibody

SorLA Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSorLA Primary Polyclonal Antibody
Also known asSorLA PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSorLA
SpecificityThis is a highly specific antibody against SorLA
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SorLA
Gene ID number79845
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Endogenous sorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function, It can also bind to RAP, It is expressed mainly in brain (cerebral cortex, SorLA, SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase, SorLa is a multifunctional endocytis receptor important in lipoprotein and protease uptake, The N-terminal propeptide, a single transmembrane receptor, also known as Sorting protein-related receptor containing LDLR class A (SorLA), binds LDL (the main cholesterol-carrying lipoprotein of plasma) and transports it into cells by endocytosis, but can also be found in liver, can be cleaved by furin or homologous proteases, cerebellum and the occipital pole), is a Type I membrane protein that may be involved in cell-cell interaction, kidney, receptor-associated protein, spinal cord, testis and pancreas, which is removed, Sortilin-related receptor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FLJ21930, FLJ39258, LDLR relative with 11 ligand binding repeats, LDLR relative with 11 ligand-binding repeats, LR 11, LR11, LRP 9, LRP9, Low density lipoprotein receptor relative with 11 ligand binding repeats, Low-density lipoprotein receptor relative with 11 ligand-binding repeats, Mosaic protein LR11, SORL 1, SORL1, SORL_HUMAN, SorLA, SorLA 1, SorLA-1, Sortilin related receptor, Sortilin related receptor LDLR class A repeats containing, Sortilin-related receptor, Sorting protein related receptor containing LDLR class A repeats, Sorting protein-related receptor containing LDLR class A repeats, gp250, C11orf32
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSorLA
Short nameSorLA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSorLA (Antibody to)
Alternative techniqueantibodies
Identity 11185
Gene SORL1
Long gene name sortilin related receptor 1
Synonyms gene C11orf32
Synonyms gene name L(DLR class) A repeats-containing , chromosome 11 open reading frame 32 sortilin-related receptor
Synonyms gp250 LR11 LRP9 SorLA SorLA-1
Synonyms name LDLR relative with 11 ligand-binding repeats
Locus 11q24, 1
Discovery year 1996-12-27
GenBank acession Y08110
Entrez gene record 6653
Pubmed identfication 9157966 8940146
RefSeq identity NM_003105
Classification Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000166057

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