Name : Srb1 Antibody
Supplier : NJS POLY
Price :406
SKU : GEN8480861917
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Srb1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications | WB |
| Recommended dilutions | 1-0, 5ug/ml, Western blot: 0 |
| Notes | Optimal dilution of the Srb1 antibody should be determined by the researcher |
| Intented use | This Srb1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q61009 |
| Purity | Antigen affinity |
| Description | It is best known for its role in facilitating the uptake of cholesteryl esters from high-density lipoproteins in the liver, SR-BI functions as a receptor for high-density lipoprotein, SR-BI has also been identified in the livers of non-mammalian species (turtle, Scavenger receptor class B, The turtle also seems to upregulate SB-RI during egg development, This movement of cholesterol is known as reverse cholesterol transport and is a protective mechanism against the development of atherosclerosis, This process drives the movement of cholesterol from peripheral tissues towards the liver for excretion, also known as SR-BI, and skate), chicken, frog, goldfish, including the liver and adrenal, indicating that cholesterol efflux may be at peak levels during developmental stages, is a protein that in humans is encoded by the SCARB1 gene, shark, suggesting it emerged early in vertebrate evolutionary history, type I (SR-BI) is an integral membrane protein found in numerous cell types/tissues, which is the principal cause of heart disease and stroke, Scavenger receptor class B member 1 (SRB1) |
| Immunogen | Amino acids KKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL of mouse Srb1 were used as the immunogen for the Srb1 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Srb1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Srb1 |
| Short name | Srb1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Srb1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1664 |
| Gene | SCARB1 |
| Long gene name | scavenger receptor class B member 1 |
| Synonyms gene | CD36L1 |
| Synonyms gene name | CD36 antigen (collagen type I receptor, member 1 , thrombospondin receptor)-like 1 scavenger receptor class B |
| Synonyms | SRB1 CLA-1 CLA1 SR-BI |
| Locus | 12q24, 31 |
| Discovery year | 1994-09-06 |
| GenBank acession | Z22555 |
| Entrez gene record | 949 |
| Pubmed identfication | 7689561 |
| RefSeq identity | NM_005505 |
| Classification | Scavenger receptors |
| Havana BLAST/BLAT | OTTHUMG00000168544 |