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SREBP-1/2 Antibody, Cy5 Conjugated

SREBP-1/2 Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, SREBP-1/2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSREBP-1/2
SpecificityThis is a highly specific antibody against SREBP-1/2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range300-350/1147
Subcellular locationIntracellular
SourceKLH conjugated synthetic peptide derived from human SREBP-1
Gene ID number6720, 6721
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Belongs to the SREBP family, Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'), COPII-coated vesicle membrane, Cytoplasmic vesicle, Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein, Golgi apparatus membrane, Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'), Interacts with LMNA, Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters, Multi-pass membrane protein, Multi-pass membrane protein, Multi-pass membrane protein, Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols, Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway, [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane, [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus, [SUBUNIT] Forms a tight complex with SCAP in the ER membrane, Transcriptional activator required for lipid homeostasis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms ADD 1, BHLHD1, D630008H06, SREBF 1, SREBF1, SREBP 1, SREBP 1c, SREBP1, Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1, Sterol regulatory element binding protein 1, Sterol regulatory element binding transcription factor 1, Sterol regulatory element binding protein 1
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSREBP-1/2 Conjugated
Short name Conjugated, SREBP-1/2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, SREBP-1/2 (Antibody to)
Alternative techniqueantibodies

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