| Long name | STAT2 Primary Polyclonal Antibody |
| Also known as | STAT2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | STAT2 |
| Specificity | This is a highly specific antibody against STAT2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 668-718/851 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human STAT2 |
| Gene ID number | 6773 |
| Swiss Prot | P52630 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Following type I IFN binding to cell surface receptors, ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, Jak kinases (TYK2 and JAK1) are activated, The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, leading to tyrosine phosphorylation of STAT1 and STAT2, that enters the nucleus, which drive the cell in an antiviral state, Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ISGF-3, STAT113, STAT2, Signal transducer and activator of transcription 2, P113 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | STAT2 |
| Short name | STAT2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 113kDa (Antibody to), signal transducer and activator on transcription 2 |
| Alternative technique | antibodies |
| Alternative to gene target | 113kDa, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0016032 and viral process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0051607 and defense response to virus and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process, ISGF-3 and P113 and STAT113, STAT2 and IDBG-40906 and ENSG00000170581 and 6773, STAT2 and IDBG-635999 and ENSBTAG00000004380 and 511023, Stat2 and IDBG-197036 and ENSMUSG00000040033 and 20847, identical protein binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0004871: signal transducer activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0042802: identical protein binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0004871: signal transducer activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0042802: identical protein binding, signal transducer and activator of transcription 2 |
| Identity | 11363 |
| Gene | STAT2 |
| Long gene name | signal transducer and activator of transcription 2 |
| Synonyms gene name | 113kD signal transducer and activator of transcription 2, 113kDa , signal transducer and activator of transcription 2 |
| Synonyms | STAT113 |
| Locus | 12q13, 2 |
| Discovery year | 1995-11-08 |
| GenBank acession | BC051284 |
| Entrez gene record | 6773 |
| Pubmed identfication | 7885841 |
| RefSeq identity | NM_005419 |
| Classification | SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000170760 |
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