Name : SUPT16H Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1203047361
| Long name | SUPT16H Primary Polyclonal Antibody |
| Also known as | SUPT16H PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SUPT16H |
| Specificity | This is a highly specific antibody against SUPT16H |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SUPT16H/CDC68 |
| Gene ID number | 11198 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, DNA replication and DNA repair, During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure, It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II), a chromatin-remodeling complex recruited by vitamin D receptor (VDR), a general chromatin factor that acts to reorganize nucleosomes, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II, which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene, Component of the FACT complex |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Chromatin specic transcription elongation factor 140 kDa subunit, Chromatin-specic transcription elongation factor 140 kDa subunit, FACT, FACT 140 kDa subunit, FACT complex subunit SPT16, FACTP140, FLJ10857, FLJ14010, Facilitates chromatin transcription complex subunit SPT16, SP16H_HUMAN, Suppressor of Ty 16 homolog, Supt16h, hSPT16, CDC68 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SUPT16H |
| Short name | SUPT16H Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SUPT16H (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11465 |
| Gene | SUPT16H |
| Long gene name | SPT16 homolog, facilitates chromatin remodeling subunit |
| Synonyms gene name | cerevisiae) , suppressor of Ty (S, cerevisiae) 16 homolog suppressor of Ty 16 homolog (S |
| Synonyms | FACT FACTP140 SPT16/CDC68 FLJ14010 FLJ10857 CDC68 |
| Synonyms name | facilitates chromatin remodeling 140 kDa subunit |
| Locus | 14q11, 2 |
| Discovery year | 1996-08-21 |
| GenBank acession | AF152961 |
| Entrez gene record | 11198 |
| Pubmed identfication | 9489704 11239457 |
| RefSeq identity | NM_007192 |
| Havana BLAST/BLAT | OTTHUMG00000029685 |