Name : Syncytin 1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6987101580
| Long name | Syncytin 1 Primary Polyclonal Antibody |
| Also known as | Syncytin 1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Syncytin 1 |
| Specificity | This is a highly specific antibody against Syncytin 1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 460-510/538 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Syncytin 1 |
| Gene ID number | 30816 |
| Swiss Prot | Q9UQF0 |
| Tested Applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | During viral and target cell membrane fusion, Endogenous envelope proteins may have kept, May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904), Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection, The formation of this structure appears to drive apposition and subsequent fusion of membranes, The protein may have at least 3 conformational states: pre-fusion native state, The surface protein (SU) mediates receptor recognition, and post-fusion hairpin state, lost or modified their original function during evolution, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain, pre-hairpin intermediate state, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, while the transmembrane protein (TM) acts as a class I viral fusion protein, This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ENVW, ERVW-1, ERVWE1, Endogenous retrovirus group W member 1, Env-W, Envelope polyprotein gPr73, Enverin, HERV-7q, HERV-7q Envelope protein, HERV-W envelope protein, HERV-W-ENV, HERV-W_7q21, HERV7Q, HERVW, HERVWENV, Syncytin, Syncytin-1, 2 provirus ancestral Env polyprotein, ENV |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Syncytin 1 |
| Short name | Syncytin 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Syncytin 1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13525 |
| Gene | ERVW-1 |
| Long gene name | endogenous retrovirus group W member 1 |
| Synonyms gene | ERVWE1 |
| Synonyms gene name | endogenous retroviral family W, env(C7), member 1 , member 1 endogenous retrovirus group W |
| Synonyms | HERV-W HERV-W-ENV HERVW HERV-7q |
| Synonyms name | envelope protein HERV-W Env glycoprotein enverin syncytin-1 HERV-tryptophan envelope protein HERV-W{7q21, 1} provirus ancestral Env polyprotein HERV-7q envelope protein envelope glycoprotein syncytin |
| Locus | 7q21, 2 |
| Discovery year | 2000-09-20 |
| GenBank acession | AF208161 |
| Entrez gene record | 30816 |
| Pubmed identfication | 9835022 9882319 21542922 |
| RefSeq identity | NM_014590 |
| Havana BLAST/BLAT | OTTHUMG00000131249 |