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Tal1 Antibody

Tal1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTal1 Primary Polyclonal Antibody
Also known asTal1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTal1
SpecificityThis is a highly specific antibody against Tal1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tal1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In addition, TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis, This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, making it the most frequent gain-of-function mutation observed in this disorder, Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Class A basic helix-loop-helix protein 17, SCL antibody, Stem cell protein, T cell acute lymphocytic leukemia 1, T cell acute lymphocytic leukemia 1 protein, T cell leukemia/lymphoma 5 protein, T-cell acute lymphocytic leukemia protein 1, T-cell leukemia/lymphoma protein 5, TAL 1 protein, TAL-1, TAL1_HUMAN, TCL 5, TCL5, Tal 1, Tal 1 product, tal1, bHLHa17
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTal1
Short nameTal1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameT-cell acute lymphocytic leukemia 1 (Antibody to)
Alternative techniqueantibodies
Identity 10879
Gene STIL
Long gene name SCL/TAL1 interrupting locus
Synonyms gene SIL
Synonyms gene name TAL1 (SCL) interrupting locus
Synonyms MCPH7
Locus 1p33
Discovery year 1997-11-05
GenBank acession M74558
Entrez gene record 6491
Pubmed identfication 2209547
RefSeq identity NM_003035
Havana BLAST/BLAT OTTHUMG00000007851

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