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Tau protein(Ser519) Antibody

Tau protein(Ser519) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTau protein(Ser519) Primary Polyclonal Antibody
Also known asTau protein(Ser519) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTau protein Ser519
SpecificityThis is a highly specific antibody against Tau protein Ser519
Modification(s)Phosphorylation
Modification site(s)Ser519
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser519
Gene ID number4137
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome, It expressed in neurons, PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system, Tau proteins subcellular located in the axons of neurons, The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization, and might be involved in the establishment and maintenance of neuronal polarity, in the cytoso l and in association with plasma membrane components, suggesting that tau functions as a linker protein between both, Tau proteins are important Promotes microtubule assembly and stability
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AI413597, AW045860, DDPAC, Disinhibition dementia parkinsonism amyotrophy complex, FLJ31424, FTDP 17, FTDP17, G Protein beta 1 gamma 2 subunit interacting factor 1, G protein beta1/gamma2 subunit interacting factor 1, MAPT, MAPTL, MAPTphospho 519, MGC134287, MGC138549, MGC156663, MSTD, MTBT1, MTBT2, Microtuble-associted protein Tau, Microtubule associated protein tau isoform 4, Mtapt, Neurofibrillary tangle protein, PHF tau, PHF-tau, PPND, Paired helical filament tau, RNPTAU, TAU_HUMAN, Tauopathy and respiratory failure, included, p-Tau proteinSer519, p-TauSer202, pTau, TauSer519
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTau protein(Ser519)
Short nameTau protein(Ser519) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTaurine protein(Ser519) (Antibody to)
Alternative techniqueantibodies

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