Name : TCF7L1 Antibody
Supplier : NJS POLY
Price :406
SKU : GEN2799091754
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | TCF7L1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the TCF7L1 antibody should be determined by the researcher |
| Intented use | This TCF7L1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9HCS4 |
| Purity | Antigen affinity |
| Description | HMG-box), The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence, These transcription factors are activated by beta catenin, This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors, also known as TCF7L1, is a human gene, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway, Transcription factor 7-like 1 (T-cell specific |
| Immunogen | Amino acids SFPATLHAHQALPVLQAQPLSLVTKSAH of human TCF7L1 were used as the immunogen for the TCF7L1 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TCF7L1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | Nuclear |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | TCF7L1 |
| Short name | TCF7L1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | HMG-box) (Antibody to), transcription factor 7-like 1 (T-cellular specific |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007420 and brain development and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008595 and anterior/posterior axis specification, DNA-templated and biological process this GO :0046022 and positive regulation of transcription from RNA polymerase II promoter during mitosis and biological process this GO :0048319 and axial mesoderm morphogenesis and biological process this GO :0048699 and generation of neurons and biological process this GO :0048863 and stem cell differentiation and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :2000036 and regulation of stem cell maintenance and biological process, HMG-box), TCF7L1 and IDBG-58889 and ENSG00000152284 and 83439, Tcf7l1 and IDBG-157940 and ENSMUSG00000055799 and 21415, embryo and biological process this GO :0030111 and regulation of Wnt signaling pathway and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043588 and skin development and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045892 and negative regulation of transcription, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0006325 and chromatin organization and biological process this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008013: beta-catenin binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008013: beta-catenin binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, transcription regulatory region DNA binding, transcription factor 7-like 1 (T-cell specific |
| Identity | 11640 |
| Gene | TCF7L1 |
| Long gene name | transcription factor 7 like 1 |
| Synonyms gene | TCF3 |
| Synonyms gene name | HMG-box) , transcription factor 7-like 1 (T-cell specific |
| Locus | 2p11, 2 |
| Discovery year | 1998-01-20 |
| GenBank acession | X62870 |
| Entrez gene record | 83439 |
| Pubmed identfication | 1741298 11085512 |
| RefSeq identity | NM_031283 |
| Havana BLAST/BLAT | OTTHUMG00000130026 |