Filters

TGFBR2 Antibody

TGFBR2 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTGFBR2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000-2000
NotesTitration of the TGFBR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis TGFBR2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P37173
PurityAntigen affinity
Description Alternatively spliced transcript variants encoding different isoforms have been characterized, Loeys-Deitz Aortic Aneurysm Syndrome, Mutations in this gene have been associated with Marfan Syndrome, The encoded protein is a transmembrane protein that has a protein kinase domain, This receptor/ligand complex phosphorylates proteins, and binds TGF-beta, and the development of various types of tumors, forms a heterodimeric complex with another receptor protein, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation, This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily
ImmunogenA portion of amino acids 13-40 from the human protein was used as the immunogen for this TGFBR2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TGFBR2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTGFBR2
Short nameTGFBR2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name b receptor II (70/80kDa) (Antibody to), transforming growth factor
Alternative techniqueantibodies
Alternative to gene target AAT3 and FAA3 and LDS1B and LDS2 and LDS2B and MFS2 and RIIC and TAAD2 and TGFbeta-RII and TGFR-2, BT, Cell surfaces, TGFBR2 and IDBG-23359 and ENSG00000163513 and 7048, Tgfbr2 and IDBG-203902 and ENSMUSG00000032440 and 21813, beta receptor II (70/80kDa), this GO :0001568 and blood vessel development and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0002088 and lens development in camera-type eye and biological process this GO :0002651 and positive regulation of tolerance induction to self antigen and biological process this GO :0002663 and positive regulation of B cell tolerance induction and biological process this GO :0002666 and positive regulation of T cell tolerance induction and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005026 and transforming growth factor beta receptor activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004675: transmembrane receptor protein serine/threonine kinase activity and also this GO :0004702: receptor signaling protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004872: receptor activity and also this GO :0005024: transforming growth factor beta-activated receptor activity and also this GO :0005026: transforming growth factor beta receptor activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004675: transmembrane receptor protein serine/threonine kinase activity, this GO :0004702: receptor signaling protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004872: receptor activity, this GO :0005024: transforming growth factor beta-activated receptor activity, this GO :0005026: transforming growth factor beta receptor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0005539: glycosaminoglycan binding, this GO :0016772: transferase activity, this GO :0031435: mitogen-activated protein kinase kinase kinase binding, this GO :0034713: type I transforming growth factor beta receptor binding, this GO :0034714: type III transforming growth factor beta receptor binding, this GO :0046332: SMAD binding, this GO :0046872: metal ion binding, this GO :0050431: transforming growth factor beta binding, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031435: mitogen-activated protein kinase kinase kinase binding and also this GO :0034713: type I transforming growth factor beta receptor binding and also this GO :0034714: type III transforming growth factor beta receptor binding and also this GO :0046332: SMAD binding and also this GO :0046872: metal ion binding and also this GO :0050431: transforming growth factor beta binding, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030324 and lung development and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0031100 and organ regeneration and biological process this GO :0031435 and mitogen-activated protein kinase kinase kinase binding and molecular function this GO :0032147 and activation of protein kinase activity and biological process this GO :0034713 and type I transforming growth factor beta receptor binding and molecular function this GO :0034714 and type III transforming growth factor beta receptor binding and molecular function this GO :0035162 and embryonic hemopoiesis and biological process this GO :0042060 and wound healing and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042493 and response to drug and biological process this GO :0043011 and myeloid dendritic cell differentiation and biological process this GO :0043235 and receptor complex and cellular component this GO :0043415 and positive regulation of skeletal muscle tissue regeneration and biological process this GO :0043627 and response to estrogen and biological process this GO :0045121 and membrane raft and cellular component this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0048545 and response to steroid hormone and biological process this GO :0048565 and digestive tract development and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048701 and embryonic cranial skeleton morphogenesis and biological process this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0051138 and positive regulation of NK T cell differentiation and biological process this GO :0051216 and cartilage development and biological process this GO :0060021 and palate development and biological process this GO :0060044 and negative regulation of cardiac muscle cell proliferation and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :0060425 and lung morphogenesis and biological process this GO :0060433 and bronchus development and biological process this GO :0060434 and bronchus morphogenesis and biological process this GO :0060439 and trachea morphogenesis and biological process this GO :0060440 and trachea formation and biological process this GO :0060443 and mammary gland morphogenesis and biological process this GO :0060463 and lung lobe morphogenesis and biological process this GO :0070022 and transforming growth factor beta receptor homodimeric complex and cellular component this GO :0070723 and response to cholesterol and biological process this GO :1990086 and lens fiber cell apoptotic process and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, transforming growth factor beta receptor activity, type II, type II and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0005539: glycosaminoglycan binding and also this GO :0016772: transferase activity, type II and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005539 and glycosaminoglycan binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005901 and caveola and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007182 and common-partner SMAD protein phosphorylation and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007369 and gastrulation and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0007566 and embryo implantation and biological process this GO :0007568 and aging and biological process this GO :0007584 and response to nutrient and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009749 and response to glucose and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010033 and response to organic substance and biological process this GO :0010634 and positive regulation of epithelial cell migration and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, 66001 and IDBG-644071 and ENSBTAG00000019832 and 535376, transforming growth factor
Identity 11773
Gene TGFBR2
Long gene name transforming growth factor beta receptor 2
Synonyms gene MFS2
Synonyms gene name beta receptor II (70/80kDa) transforming growth factor beta receptor II , transforming growth factor
Locus 3p24, 1
Discovery year 1993-09-30
Entrez gene record 7048
Pubmed identfication 1319842 15235604
Classification Type 2 receptor serine/threonine kinases
Havana BLAST/BLAT OTTHUMG00000130569
Locus Specific Databases Belgium The TGFBR2 mutations database LRG_779 , Ghent, LOVD - Center for Medical Genetics

Similar products

Subscribe to our Newsletter