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Thyroglobulin

Thyroglobulin size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asThyroglobulin
Other names N/A, Thyroglobulin, thyroglobulin, thyroglobulin, thyroglobulin
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameTG
Gene name synonimsN/A
Other gene names AITD3, TG, TGN, Tg, TG
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG1
Clone6E 1
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Adenocarcinomas of other-than-thyroid origin do not react with this antibody, Anti-thyroglobulin, Furthermore, It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine, Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative, Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor, Prior to forming dimers, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally, This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types, This particular antibody might cross react with speacies outside of the listed ones, anti-thyroglobulin, can be a reliable marker to differentiate between primary thyroid and lung neoplasms, can identify medullary carcinomas of the thyroid, combined with anti-TTF1, combined with anti-calcitonin, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation, Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Flow Cytometry (FC/FACS), Western Blot (WB) Immunohistology (IH), ELISA (EIA)
Gene targetThyroglobulin
Short nameThyroglobulin
Alternative nameThyroglobulin
Identity 11764
Gene TG
Long gene name thyroglobulin
Synonyms TGN AITD3
Locus 8q24, 22
Discovery year 2001-06-22
GenBank acession AU141420
Entrez gene record 7038
RefSeq identity NM_003235
Havana BLAST/BLAT OTTHUMG00000164649

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