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TIGIT Antibody

TIGIT Antibody size: 0.05 ml 199

Supplier NJS POLY
Price 199
Size 0.05 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTIGIT
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutionsWestern blot: 1:2000
NotesTitration of the TIGIT antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis TIGIT antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q495A1
PurityAntigen affinity
DescriptionTIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
ImmunogenA portion of amino acids 12-142 from the human protein was used as the immunogen for this TIGIT antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TIGIT antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTIGIT
Short nameTIGIT Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameT cellular immunoreceptor including Ig and ITIM domains (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Cell surfaces, TIGIT and IDBG-50851 and ENSG00000181847 and 201633, TIGIT and IDBG-632631 and ENSBTAG00000011921 and 100140801, Tigit and IDBG-161101 and ENSMUSG00000071552 and 100043314, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, T cell immunoreceptor with Ig and ITIM domains
Identity 26838
Gene TIGIT
Long gene name T-cell immunoreceptor with Ig and ITIM domains
Synonyms gene VSIG9 VSTM3
Synonyms gene name V-set and immunoglobulin domain containing 9 V-set and transmembrane domain containing 3 T cell immunoreceptor with Ig and ITIM domains
Synonyms FLJ39873 DKFZp667A205
Locus 3q13, 31
Discovery year 2006-02-07
GenBank acession AK097192
Entrez gene record 201633
Pubmed identfication 19011627
RefSeq identity NM_173799
Classification V-set domain containing
Havana BLAST/BLAT OTTHUMG00000159331

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