Name : TLE1 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN7676596652
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | TLE1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB, IF |
| Recommended dilutions | Immunofluorescence: 1:25, Western blot: 1:1000 |
| Notes | Titration of the TLE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This TLE1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q04724 |
| Purity | Antigen affinity |
| Description | Inhibits NF-kappa-B-regulated gene expression, Inhibits the transcriptional activation mediated by FOXA2, The effects of full-length TLE family members may be modulated by association with dominant-negative AES, Unusual function as coactivator for ESRRG, and by CTNNB1 and TCF family members in Wnt signaling, Transcriptional corepressor that binds to a number of transcription factors |
| Immunogen | This TLE1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 187-221 amino acids from the N-terminal region of human TLE1 |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TLE1 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | TLE1 |
| Short name | TLE1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | TLE1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11837 |
| Gene | TLE1 |
| Long gene name | transducin like enhancer of split 1 |
| Synonyms gene name | Drosophila) , transducin-like enhancer of split 1 (E(sp1) homolog |
| Synonyms | ESG1 GRG1 ESG |
| Synonyms name | enhancer of split groucho 1 |
| Locus | 9q21, 32 |
| Discovery year | 1993-12-13 |
| Entrez gene record | 7088 |
| Pubmed identfication | 8365415 8808280 |
| RefSeq identity | NM_005077 |
| Classification | WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000021008 |