| Alternative name1 | CD283, CD283 Antigen), TLR 3, TLR-3, Toll-like Receptor 3, Anti-TLR3 (Toll Like Receptor 3 |
| Alternative name2 | CD283, CD283 Antigen), TLR 3, TLR-3, Toll-like Receptor 3, TLR3 (Toll Like Receptor 3 |
| Alternative name3 | CD283, CD283 Antigen), TLR 3, TLR-3, Toll-like Receptor 3, TLR3 (Toll Like Receptor 3 |
| Alternative name4 | TLR3 |
| Alternative name5 | CD283, CD283 Antigen), TLR 3, TLR-3, Toll-like Receptor 3, Anti -TLR3 (Toll Like Receptor 3 |
| Other names | N/A, TLR3 |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | N/A |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Mouse, Human |
| Specificity and cross-reactivity | Species Crossreactivity: mouse, Recognizes human CD283 |
| Purification method | Highly Purified by Ion Exchange chromatography |
| Form/Appearance | 0, 02% sodium azide, Supplied as a liquid in PBS |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile 40-50% glycerol, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | CD283, CD283, TLR 3, TLR-3, Toll-like Receptor 3, TLR3 (Toll Like Receptor 3 |
| Short name | CD283, CD283 Antigen) Antibody, TLR 3, TLR-3, Toll-like Receptor 3, TLR3 (Toll Like Receptor 3 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD283, CD283 protein) (Antibody to), Toll-like Receptor 3, Toll-like receptor 3, Toll-like receptor-3, toll-like receptor 3 (Toll Like Receptor 3 |
| Alternative technique | antibodies |
| Alternative to gene target | CD283 and IIAE2, Cell surfaces, TLR3 and IDBG-47294 and ENSG00000164342 and 7098, TLR3 and IDBG-628571 and ENSBTAG00000008682 and 281535, Tlr3 and IDBG-152685 and ENSMUSG00000031639 and 142980, protein binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002282 and microglial cell activation involved in immune response and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003725 and double-stranded RNA binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006952 and defense response and biological process this GO :0006954 and inflammatory response and biological process this GO :0006972 and hyperosmotic response and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008584 and male this GO nad development and biological process this GO :0009597 and detection of virus and biological process this GO :0009615 and response to virus and biological process this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034123 and positive regulation of toll-like receptor signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034346 and positive regulation of type III interferon production and biological process this GO :0035458 and cellular response to interferon-beta and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035690 and cellular response to drug and biological process this GO :0036020 and endolysosome membrane and cellular component this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043331 and response to dsRNA and biological process this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045080 and positive regulation of chemokine biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045671 and negative regulation of osteoclast differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071359 and cellular response to dsRNA and biological process this GO :0071360 and cellular response to exogenous dsRNA and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097527 and necroptotic signaling pathway and biological process, this GO :0003725: double-stranded RNA binding, this GO :0003725: double-stranded RNA binding and also this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding, this GO :0004872: receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005515: protein binding, toll-like receptor 3 |
| Identity | 11849 |
| Gene | TLR3 |
| Long gene name | toll like receptor 3 |
| Synonyms gene name | toll-like receptor 3 |
| Synonyms | CD283 |
| Locus | 4q35, 1 |
| Discovery year | 1998-06-25 |
| GenBank acession | U88879 |
| Entrez gene record | 7098 |
| Pubmed identfication | 9435236 |
| Classification | CD molecules Toll like receptors |
| Havana BLAST/BLAT | OTTHUMG00000160345 |
| Locus Specific Databases | TLR3base: Mutation registry for Influenza-associated encephalopathy LRG_117 |
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