Name : TLR8, ~120kD, Clone: 44C143, Mouse Monoclonal antibody-Human; WB/FACS
Supplier : ACCURATE MONOCLONALS
Price :877
SKU : GEN1252118994
| Alternative name 1 | Clone: 44C143, Mab anti-Human, WB/FACS, ~120kD, TLR8 |
| Alternative name 2 | Clone: 44C143, Mab antibody-Human, WB/FACS, ~120kD, TLR8 |
| Alternative name 3 | Clone: 44C143, Mab antibody-Homo sapiens, WB/FACS, ~120kD, TLR8 |
| Alternative name 4 | anti-TLR8 ~120kD Clone: 44C143 /FACS |
| Alternative name 5 | TLR8 ~120kD Clone: 44C143 /FACS |
| Clonality | Monoclonal Antibody |
| Description | Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling | Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory | For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or  |
| Latin name | Mus musculus |
| French translation | anticorps |
| Gene target | 44C143, Monoclonal /FACS, ~120kD, TLR8 |
| Short name | Clone: 44C143, Mouse Monoclonal antibody- /FACS, ~120kD, TLR8 |
| Technique | Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species | Humans, Mouses, Human |
| Alternative name | Mouse monoclonal (Antibody to)-H, Western Blot/flow cytometer cell sorting, clonality: 44C143, sapiens, ~120kD, toll-like receptor 8 |
| Alternative technique | murine |
| Alternative to gene target | Plasma membranes, TLR8 and IDBG-44288 and ENSG00000101916 and 51311, Tlr8 and IDBG-185523 and ENSMUSG00000040522 and 170744, drug binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0003723 and RNA binding and molecular function this GO :0003725 and double-stranded RNA binding and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0008144 and drug binding and molecular function this GO :0009615 and response to virus and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0034158 and toll-like receptor 8 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0036020 and endolysosome membrane and cellular component this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045089 and positive regulation of innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0051607 and defense response to virus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003723: RNA binding and also this GO :0003725: double-stranded RNA binding and also this GO :0003727: single-stranded RNA binding and also this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0008144: drug binding, this GO :0003723: RNA binding, this GO :0003725: double-stranded RNA binding, this GO :0003727: single-stranded RNA binding, this GO :0004872: receptor activity, this GO :0005515: protein binding, this GO :0008144: drug binding, toll-like receptor 8 |
| Identity | 15632 |
| Gene | TLR8 |
| Long gene name | toll like receptor 8 |
| Synonyms gene name | toll-like receptor 8 |
| Synonyms | CD288 |
| Locus | Xp22, 2 |
| Discovery year | 2001-04-27 |
| GenBank acession | AF246971 |
| Entrez gene record | 51311 |
| Pubmed identfication | 11022119 |
| RefSeq identity | NM_016610 |
| Classification | CD molecules Toll like receptors |
| Havana BLAST/BLAT | OTTHUMG00000021145 |
| Locus Specific Databases | Mental Retardation database |