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TNFR Antibody

TNFR Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTNFR
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the TNFR antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis TNFR antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P19438
PurityAntigen affinity
Description Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome, The impaired receptor clearance is thought to be a mechanism of the disease, This protein is one of the major receptors for the tumor necrosis factor-alpha, This receptor can activate NF-kappaB, and function as a regulator of inflammation, and thus play regulatory roles in the signal transduction mediated by the receptor, mediate apoptosis, The protein encoded by this gene is a member of the TNF-receptor superfamily
ImmunogenA portion of amino acids 17-43 from the human protein was used as the immunogen for this TNFR antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TNFR antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTNFR
Short nameTNFR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTNFR (Antibody to)
Alternative techniqueantibodies
Identity 6718
Gene LTBR
Long gene name lymphotoxin beta receptor
Synonyms gene D12S370
Synonyms TNFCR TNFR-RP TNFR2-RP TNF-R-III TNFRSF3
Synonyms name TNFR superfamily, member 3
Locus 12p13
Discovery year 1996-03-12
GenBank acession L04270
Entrez gene record 4055
Pubmed identfication 8171323 8486360
Classification Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000168356

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